Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TEK | Q02763 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12689500 | 0.81 | ALDH1A1 (0.36) | AURKAKDM4ETEKALDH1A1KCNH2 | |
| SCHEMBL30176714 | 0.76 | CTSS (0.49) | TEKPARP1ALDH1A1CTSSCTSK | |
| SCHEMBL21906548 | 0.74 | ALDH1A1 (0.39) | METAP2KDM4EALDH1A1MAPTPIK3CA | |
| SCHEMBL29658121 | 0.73 | ALDH1A1 (0.33) | METAP2KDM4EPARP1ALDH1A1PIK3CA | |
| SCHEMBL3229989 | 0.71 | KDM4E (0.50) | AURKAKDM4EALDH1A1HTTHSD17B10 | |
| SCHEMBL11773659 | 0.70 | HSD17B10 (0.70) | AURKAMETAP2KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL324998 | 0.69 | ALDH1A1 (0.39) | KDM4EALDH1A1MAPTPIK3CA | |
| SCHEMBL620396 | 0.69 | SMN1; SMN2 (0.48) | AURKAMETAP2KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL2190488 | 0.69 | ALDH1A1 (0.48) | KDM4EPARP1ALDH1A1HTTMAPT | |
| SCHEMBL8367003 | 0.69 | KDM4E (0.39) | AURKAMETAP2KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166156-B | Tyrosine kinase inhibitors, compositions and methods | 贝达药业股份有限公司 | 2024-02-27 | — | — | CN | claimed |
| JP-62195379-A | — | — | None | — | — | JP | disclosed |
| US-12144349-B2 | Pesticidal mixtures comprising a mesoionic compound | BASF SE (DE) | 2024-11-19 | — | — | US | disclosed |
| CN-113166156-B | Tyrosine kinase inhibitors, compositions and methods | 贝达药业股份有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-117355519-A | Novel substituted pyridines as fungicides | 巴斯夫欧洲公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-110526911-B | Pesticidally active heterocyclic derivatives with sulfur-containing substituents | 先正达参股股份有限公司 | 2022-09-13 | — | — | CN | disclosed |
| JP-S62195379-A | 6-TRIFLUOROMETHYLIMIDAZO(4,5-B)PYRIDINE COMPOUND AND NOXIOUS-LIFE CONTROLLING AGENT CONTAINING SAME | ISHIHARA SANGYO KAISHA LTD | 1987-08-28 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12144349-B2 | Pesticidal mixtures comprising a mesoionic compound | ACHE, DDT, MTX2 | AURKA 2558/4885METAP2 5/4885KDM4E 4556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.