Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | REN | P00797 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 3/20 | 0.46 |
| ▸ | CTSB | P07858 | 4/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 4/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | NMBR | P28336 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10725297 | 0.92 | CASP3 (0.50) | CASP3RENCASP1CTSBCTSK | |
| SCHEMBL10725301 | 0.92 | CASP3 (0.50) | CASP3RENCASP1CTSBCTSK | |
| SCHEMBL10720671 | 0.87 | CTSB (0.51) | CASP3RENCASP1CTSBCTSK | |
| SCHEMBL10639324 | 0.85 | REN (0.52) | CASP3RENCASP1CTSBCTSK | |
| SCHEMBL10724728 | 0.84 | REN (0.59) | CASP3RENCTSBCTSK | |
| SCHEMBL10724731 | 0.84 | REN (0.59) | CASP3RENCTSBCTSK | |
| SCHEMBL10869262 | 0.84 | HRH4 (0.45) | RENCTSBCTSKCTSSHRH4 | |
| SCHEMBL10722651 | 0.83 | CASP1 (0.46) | CASP3RENCASP1CTSBCTSK | |
| SCHEMBL10720680 | 0.82 | CTSK (0.60) | CASP3RENCTSBCTSKCTSL | |
| SCHEMBL10720786 | 0.82 | MC4R (0.56) | CASP3RENCASP1CTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4698329-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1987-10-06 | — | — | US | disclosed |
| EP-0152255-A2 | New renin-inhibitory peptides and their use | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |