Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL8586406 | 0.97 | CA4 (0.32) | CA4FAHD1 | |
| SCHEMBL5900871 | 0.97 | CA4 (0.39) | CA4FAHD1 | |
| SCHEMBL973725 | 0.73 | CA2 (0.33) | CA2 | |
| Trifluoroacetic Acid SCHEMBL108536 | 0.72 | — | — | |
| SCHEMBL9455389 | 0.71 | — | — | |
| SCHEMBL2776908 | 0.71 | — | — | |
| SCHEMBL864818 | 0.71 | — | — | |
| SCHEMBL1930049 | 0.71 | — | — | |
| SCHEMBL203037 | 0.71 | — | — | |
| SCHEMBL14146053 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62241906-A | — | — | None | — | — | JP | disclosed |
| JP-S62241906-A | FLUORINE-CONTAINING POLYMER | TOSOH CORP | 1987-10-22 | — | — | JP | disclosed |