Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716377 | 0.79 | MAPT (0.56) | MAPTKMT2AKDM4EPKMLMNA | |
| SCHEMBL10730963 | 0.79 | MAPT (0.45) | MAPTMEN1KMT2AKDM4EGAA | |
| SCHEMBL10730881 | 0.77 | MAPT (0.54) | MAPTKDM4EPKMLMNAHPGD | |
| SCHEMBL10730384 | 0.75 | MAPT (0.56) | MAPTMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL18984723 | 0.75 | MAPT (0.52) | MAPTMEN1KMT2AKDM4EGAA | |
| SCHEMBL28946370 | 0.73 | MEN1 (0.83) | MEN1KMT2ASLC40A1G6PDNFKBIA | |
| SCHEMBL10716650 | 0.72 | MAPT (0.78) | MAPTMEN1KMT2APKMLMNA | |
| SCHEMBL10717698 | 0.72 | MAPT (0.72) | MAPTMEN1KMT2AGAAPKM | |
| SCHEMBL10726355 | 0.71 | MAPT (0.55) | MAPTKDM4EGAAPKMLMNA | |
| SCHEMBL10716454 | 0.70 | POLB (0.50) | MAPTMEN1KMT2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | claimed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |