Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10726134 | 0.79 | MAPT (0.49) | MAPTSMN1; SMN2ATMALDH1A1LMNA | |
| SCHEMBL10716377 | 0.75 | MAPT (0.56) | MAPTSMN1; SMN2ATMALDH1A1LMNA | |
| SCHEMBL10731727 | 0.73 | PKM (0.49) | MAPTALDH1A1LMNAPKMHPGD | |
| SCHEMBL10730881 | 0.73 | MAPT (0.54) | MAPTSMN1; SMN2ALDH1A1LMNAPKM | |
| SCHEMBL10730384 | 0.71 | MAPT (0.56) | MAPTSMN1; SMN2ATMALDH1A1KMT2A | |
| SCHEMBL10716650 | 0.68 | MAPT (0.78) | MAPTALDH1A1LMNAPKMHPGD | |
| SCHEMBL10730781 | 0.68 | MAPT (0.58) | MAPTSMN1; SMN2ALDH1A1LMNAPKM | |
| SCHEMBL10726355 | 0.68 | MAPT (0.55) | MAPTALDH1A1LMNAPKMHPGD | |
| SCHEMBL10719098 | 0.67 | MAPT (0.54) | MAPTSMN1; SMN2ATMALDH1A1LMNA | |
| SCHEMBL10716454 | 0.67 | POLB (0.50) | MAPTSMN1; SMN2ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | claimed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |