Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10730420 | 0.88 | L3MBTL1 (0.42) | CYP1A2ALDH1A1SMN1; SMN2TP53CYP3A4 | |
| SCHEMBL11096193 | 0.84 | CYP1A2 (0.42) | MAP4K4CYP1A2ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL11403854 | 0.84 | MAP4K4 (0.43) | MAP4K4CYP1A2ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL9617193 | 0.82 | FFAR2 (0.42) | ALDH1A1SMN1; SMN2LMNATDP1 | |
| SCHEMBL11264919 | 0.81 | CYP1A2 (0.51) | MAP4K4CYP1A2ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL10736012 | 0.80 | CYP1A2 (0.52) | MAP4K4CYP1A2ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL11272939 | 0.80 | CYP1A2 (0.39) | MAP4K4CYP1A2ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL9491546 | 0.78 | PTGS2 (0.41) | ALDH1A1MAPTFGFR4 | |
| SCHEMBL11099030 | 0.77 | PPARG (0.42) | MAP4K4CYP1A2ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL11235798 | 0.77 | ALDH1A1 (0.55) | MAP4K4CYP1A2ALDH1A1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4675047-A | MONOCOTYLEDON WEES | ICI AUSTRALIA LIMITED, 1 NICHOLSON ST., MELBOURNE, VICTORIA, 3000, AUSTRALIA, A CORP. OF AUSTRALIA | 1987-06-23 | — | — | US | claimed |
| EP-0044163-A2 | Quinazolinyloxy(amino)phenoxyalkane carboxylic acid derivatives, process for their synthesis, herbicidal compositions containing them and their use as herbicides | ICI AUSTRALIA LIMITED (AU) | 1982-01-20 | — | — | EP | claimed |