Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | PAM | P19021 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6226660 | 0.88 | ALDH1A1 (0.39) | CES1CES2AKR1B1MEN1KMT2A | |
| SCHEMBL1903673 | 0.69 | CA2 (0.33) | CES1CES2TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL589981 | 0.69 | CES1 (0.46) | CES1CES2AKR1B1MEN1KMT2A | |
| SCHEMBL6228738 | 0.67 | CES2 (0.34) | CES1CES2TSHRALDH1A1 | |
| SCHEMBL2806134 | 0.61 | MAOB (0.41) | MEN1KMT2ATDP1CALM1 | |
| SCHEMBL351698 | 0.61 | CES1 (0.60) | CES1CES2AKR1B1MEN1KMT2A | |
| SCHEMBL4981463 | 0.61 | CES1 (0.60) | CES1CES2AKR1B1MEN1KMT2A | |
| SCHEMBL5071007 | 0.61 | CES1 (0.60) | CES1CES2AKR1B1MEN1KMT2A | |
| SCHEMBL11389692 | 0.60 | CES1 (0.52) | CES1CES2AKR1B1MEN1KMT2A | |
| SCHEMBL311140 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11492471-B2 | Polypropylene resin composition and monolayer and multilayer film | MITSUI CHEMICALS, INC. (JP) | 2022-11-08 | — | — | US | disclosed |
| US-20190300688-A1 | POLYPROPYLENE RESIN COMPOSITION AND MONOLAYER AND MULTILAYER FILM | MITSUI CHEMICALS, INC. (JP) | 2019-10-03 | — | — | US | disclosed |
| EP-2511305-B1 | Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same | MITSUI CHEMICALS INC (JP) | 2019-05-29 | — | — | EP | disclosed |
| EP-1548018-B1 | CROSSLINKED METALLOCENE COMPOUND FOR OLEFIN POLYMERIZATION AND METHOD OF POLYMERIZING OLEFIN WITH THE SAME | MITSUI CHEMICALS INC (JP) | 2018-10-10 | — | — | EP | disclosed |
| WO-2017121756-A1 | PIPES COMPRISING SYNDIOTACTIC POLYPROPYLENE | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2017-07-20 | — | — | WO | disclosed |
| US-8716418-B2 | Process for producing syndiotactic α-olefin polymer | MITSUI CHEMICALS, INC. (JP) | 2014-05-06 | — | — | US | disclosed |
| US-20120283399-A1 | PROCESS FOR PRODUCING SYNDIOTACTIC alpha-OLEFIN POLYMER | MITSUI CHEMICALS, INC. | 2012-11-08 | — | — | US | disclosed |
| EP-2511305-A1 | Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same | Mitsui Chemicals, Inc. (JP) | 2012-10-17 | — | — | EP | disclosed |
| EP-2465878-A1 | Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same | Mitsui Chemicals, Inc. (JP) | 2012-06-20 | — | — | EP | disclosed |
| EP-2465879-A1 | Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same | Mitsui Chemicals, Inc. (JP) | 2012-06-20 | — | — | EP | disclosed |
| WO-2011019541-A1 | PROCESSES FOR CONTROLLING THE VISCOSITY OF POLYALPHAOLEFINS | CHEMTURA CORPORATION (US) | 2011-02-17 | — | — | WO | disclosed |
| US-7880047-B2 | continuous addition polymerization of polydecene in the presence of the saturated n-decane, the hydrogen, and the catalyst system; selectively adsorb spent catalyst; controlling viscosity | CHEMTURA CORPORATION (US) | 2011-02-01 | — | — | US | disclosed |
| EP-2274344-A1 | POLYALPHAOLEFINS AND PROCESSES FOR FORMING POLYALPHAOLEFINS | Chemtura Corporation (US) | 2011-01-19 | — | — | EP | disclosed |
| US-20060161013-A1 | Crosslinked metallocene compound for olefin polymerization and method of polymerizing olefin with the same | MITSUI CHEMICALS, INC. (JP) | 2006-07-20 | — | — | US | disclosed |
| EP-1548018-A1 | CROSSLINKED METALLOCENE COMPOUND FOR OLEFIN POLYMERIZATION AND METHOD OF POLYMERIZING OLEFIN WITH THE SAME | Mitsui Chemicals, Inc. (JP) | 2005-06-29 | — | — | EP | disclosed |
| EP-0892816-B1 | POLYMERIZATION PROCESS FOR PRODUCING POLYOLEFIN ELASTOMER, CATION-GENERATING COCATALYST FOR ACTIVATING A METALLOCENE PROCATALYST, POLYOLEFIN ELASTOMER POSSESSING A UNIQUE COMBINATION OF PROPERTIES AND PRODUCTS MANUFACTURED THEREFROM | UNIROYAL CHEM CO INC (US) | 2002-12-04 | — | — | EP | disclosed |
| US-6060572-A | LIQUID PHASE POLYMERIZATION OF ETHYLENE AND AT LEAST ONE OTHER ALPHA-OLEFIN USING A BULKY METALLOCENE CATALYST ACTIVATED BY AN ALUMOXANE OR A CATION-GENERATING METALLOCENE; HIGH MOLECULAR WEIGHT; HIGH VISCOSITY; LOW POLYDISPERSITY | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2000-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060161013-A1 | Crosslinked metallocene compound for olefin polymerization and method of polymerizing olefin with the same | PCNA, MACF1, PIN1 | CES1 2357/4885CES2 895/4885AKR1B1 3351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.