Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 1/20 | 0.56 |
| ▸ | IAPP | P10997 | 2/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | F13A1 | P00488 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL107381 | 0.90 | IAPP (0.65) | F2RL1IAPPTRPV1HDAC2HDAC8 | |
| Letestuianin C SCHEMBL4410123 | 0.90 | F2RL1 (0.60) | F2RL1TRPV1HDAC2HDAC8ALOX5 | |
| SCHEMBL1645396 | 0.83 | KDM4E (0.55) | F2RL1TRPV1HDAC2HDAC8ALOX5 | |
| SCHEMBL13311578 | 0.83 | TRPV1 (0.64) | F2RL1TRPV1HDAC2HDAC8CYP19A1 | |
| SCHEMBL8108885 | 0.82 | ESR1 (0.62) | F2RL1IAPPTRPV1HDAC2HDAC8 | |
| SCHEMBL2862583 | 0.81 | MMP12 (0.68) | F2RL1TRPV1HDAC2HDAC8KDM4E | |
| SCHEMBL1053043 | 0.81 | IAPP (0.66) | F2RL1IAPPTRPV1HDAC2HDAC8 | |
| SCHEMBL28349297 | 0.81 | IAPP (0.84) | IAPPTRPV1ALOX5OR51E2KDM4E | |
| SCHEMBL31322120 | 0.80 | F2RL1 (0.64) | F2RL1TRPV1HDAC2HDAC8ALOX5 | |
| SCHEMBL3754312 | 0.80 | CYP4F2 (0.57) | F2RL1TRPV1HDAC2HDAC8ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105073757-B | Dyeing process using a hair-dyeing precursor obtained from an iridoid, composition, precursor and device comprising such a precursor | 莱雅公司 | 2019-12-17 | — | — | CN | disclosed |
| US-20090318565-A1 | Novel Compositions for the Enhancement of the Anti-oxidant Potential of Hydrogenated Curcuminoids or Combinations Thereof | MAJEED MUHAMMED | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318565-A1 | Novel Compositions for the Enhancement of the Anti-oxidant Potential of Hydrogenated Curcuminoids or Combinations Thereof | GPX4, HMOX1, GPX1 | F2RL1 4334/4885IAPP 2035/4885TRPV1 2279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.