Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13311578 | 0.92 | TRPV1 (0.64) | F2RL1HDAC2HDAC8CYP19A1ALDH1A1 | |
| SCHEMBL8108885 | 0.91 | ESR1 (0.62) | F2RL1HDAC2HDAC8ESR1ESR2 | |
| SCHEMBL4409944 | 0.90 | F2RL1 (0.56) | F2RL1HDAC2HDAC8ESR1ESR2 | |
| SCHEMBL2862583 | 0.90 | MMP12 (0.68) | F2RL1HDAC2HDAC8ESR1ESR2 | |
| SCHEMBL31322120 | 0.89 | F2RL1 (0.64) | F2RL1HDAC2HDAC8ESR1ESR2 | |
| SCHEMBL1645396 | 0.88 | KDM4E (0.55) | F2RL1HDAC2HDAC8ESR1ESR2 | |
| SCHEMBL12601802 | 0.87 | IAPP (0.65) | ESR1KDM4ECYP19A1MEN1KMT2A | |
| SCHEMBL15936319 | 0.86 | TRPV1 (0.63) | HDAC2HDAC8MAPK1MMP12TRPV1 | |
| SCHEMBL3217413 | 0.86 | BACE1 (0.53) | F2RL1HDAC2HDAC8MEN1KMT2A | |
| SCHEMBL452806 | 0.84 | TDP1 (0.59) | HDAC2HDAC8ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4045478-B1 | CURCUMINOID COMPOSITION AND ITS THERAPEUTIC POTENTIAL IN MANAGING LUNG FIBROSIS | SAMI SABINSA GROUP LTD (IN) | 2026-01-28 | — | — | EP | claimed |
| EP-4045478-A1 | CURCUMINOID COMPOSITION AND ITS THERAPEUTIC POTENTIAL IN MANAGING LUNG FIBROSIS | Sami-Sabinsa Group Limited (IN) | 2022-08-24 | — | — | EP | claimed |
| CN-114246849-A | Curcumin-peptide conjugates and formulations thereof | 奥斯生化药剂公司 | 2022-03-29 | — | — | CN | claimed |
| US-20090318565-A1 | Novel Compositions for the Enhancement of the Anti-oxidant Potential of Hydrogenated Curcuminoids or Combinations Thereof | MAJEED MUHAMMED | 2009-12-24 | — | — | US | claimed |
| US-6875426-B2 | Self-tanning composition containing a tetrahydrocurcuminoid and a self-tanning agent | L'OREAL (FR) | 2005-04-05 | — | — | US | claimed |
| US-6872401-B2 | Cosmetic/dermatological compositions comprising a tetrahydrocurcuminoid and an amide oil | L'OREAL (FR) | 2005-03-29 | — | — | US | claimed |
| US-20040009200-A1 | Cosmetic/dermatological compositions comprising a tetrahydrocurcuminoid and an amide oil | SOCIETE L'OREAL S.A. (FR) | 2004-01-15 | — | — | US | claimed |
| US-20030228268-A1 | Self-tanning composition containing a tetrahydrocurcuminoid and a self-tanning agent | SOCIETE L'OREAL S.A. (FR) | 2003-12-11 | — | — | US | claimed |
| EP-1348424-A1 | Self-tanning composition containing a tetrahydrocurcumine derivative and a self-tanning agent | L'OREAL (FR) | 2003-10-01 | — | — | EP | claimed |
| EP-1348418-A1 | Cosmetical or dermatological composition containing a tetrahydrocurcumin derivative and an oil bearing an amide group | L'OREAL (FR) | 2003-10-01 | — | — | EP | claimed |
| EP-4743071-A2 | DIPHENYLETHYLENE COMPOUNDS AND COMPOSITIONS THEREOF | INNOVENE INC. (US) | 2026-05-20 | — | — | EP | disclosed |
| EP-4045478-B1 | CURCUMINOID COMPOSITION AND ITS THERAPEUTIC POTENTIAL IN MANAGING LUNG FIBROSIS | SAMI SABINSA GROUP LTD (IN) | 2026-01-28 | — | — | EP | disclosed |
| US-20250206788-A1 | CURCUMIN-PEPTIDE CONJUGATES AND FORMULATIONS THEREOF | CHANCEY, John (US) | 2025-06-26 | — | — | US | disclosed |
| US-12247054-B2 | Curcumin-peptide conjugates and formulations thereof | HAUS BIOCEUTICALS, INC. | 2025-03-11 | — | — | US | disclosed |
| WO-2025015023-A2 | DIPHENYLETHYLENE COMPOUNDS AND COMPOSITIONS THEREOF | INNOVENE, INC. (US) | 2025-01-16 | — | — | WO | disclosed |
| US-5208251-A | Compounds for antiinflammatory agents, antiallergens, antiarthritic, antiulcer agents | WARNER-LAMBERT COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0245825-B1 | STYRYL PYRAZOLES, ISOXAZOLES AND ANALOGS THEREOF HAVING ACTIVITY AS 5-LIPOXY-GENASE INHIBITORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | WARNER-LAMBERT COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| US-4924002-A | REACTION WITH MOLYBDENUM CARBONYL AND HYDRAZINE | WARNER-LAMBERT COMPANY (US) | 1990-05-08 | — | — | US | disclosed |
| US-4877881-A | SUNSCREEN | WARNER-LAMBERT COMPANY (US) | 1989-10-31 | — | — | US | disclosed |
| EP-0245825-A1 | Styryl pyrazoles, isoxazoles and analogs thereof having activity as 5-lipoxy-genase inhibitors and pharmaceutical compositions containing them | WARNER-LAMBERT COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030228268-A1 | Self-tanning composition containing a tetrahydrocurcuminoid and a self-tanning agent | TYR, TES, TERT | F2RL1 3615/4885HDAC2 2042/4885HDAC8 1229/4885 |
| US-20090318565-A1 | Novel Compositions for the Enhancement of the Anti-oxidant Potential of Hydrogenated Curcuminoids or Combinations Thereof | GPX4, HMOX1, GPX1 | F2RL1 4334/4885HDAC2 748/4885HDAC8 1026/4885 |
| US-20040009200-A1 | Cosmetic/dermatological compositions comprising a tetrahydrocurcuminoid and an amide oil | KRT18, DHCR24, FABP4 | F2RL1 1733/4885HDAC2 1687/4885HDAC8 1098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.