Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11773094 | 0.83 | RAB9A (0.49) | CFTRHTTPOLBGAAMRGPRX4 | |
| SCHEMBL10745596 | 0.80 | L3MBTL1 (0.49) | CFTRHTTPOLBGAAMRGPRX4 | |
| SCHEMBL10835052 | 0.76 | KCNQ3 (0.46) | CFTRPOLBGAAMRGPRX4HSD17B10 | |
| SCHEMBL11703013 | 0.76 | KCNQ3 (0.53) | CFTRHTTPOLBGAAMRGPRX4 | |
| SCHEMBL10741661 | 0.74 | MAPT (0.53) | CFTRHTTGAAMRGPRX4LMNA | |
| SCHEMBL10744540 | 0.74 | CFTR (0.47) | CFTRHTTPOLBGAAMRGPRX4 | |
| SCHEMBL3269027 | 0.73 | PPARD (0.50) | — | |
| SCHEMBL3269029 | 0.73 | PPARD (0.50) | — | |
| SCHEMBL10747092 | 0.72 | CFTR (0.48) | CFTRHTTGAAMRGPRX4CYP1A2 | |
| SCHEMBL10741387 | 0.72 | L3MBTL1 (0.47) | CFTRHTTGAAMRGPRX4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4663344-A | ANTIPYRETICS, ANTIARTHRITIC AGENTS | MERCK & CO., INC. (US) | 1987-05-05 | — | — | US | disclosed |