Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.54 |
| ▸ | EGFR | P00533 | 3/20 | 0.49 |
| ▸ | FLT1 | P17948 | 4/20 | 0.48 |
| ▸ | FLT4 | P35916 | 4/20 | 0.48 |
| ▸ | KDR | P35968 | 4/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10740058 | 0.76 | PTGS2 (0.66) | PTGS2PTGS1EGFRFLT1FLT4 | |
| SCHEMBL10744485 | 0.74 | PTGS2 (0.63) | PTGS2PTGS1EGFRFLT1FLT4 | |
| SCHEMBL6505475 | 0.72 | TAS1R3 (0.56) | GAAKDRTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL5480908 | 0.72 | ALDH1A1 (0.57) | GAATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL15628994 | 0.72 | RORC (0.71) | — | |
| SCHEMBL8299877 | 0.72 | BCL2L1 (0.56) | PTGS2PTGS1EGFRFLT1FLT4 | |
| SCHEMBL13329865 | 0.71 | CA1 (0.59) | GAAPTGS2PTGS1EGFRERBB2 | |
| SCHEMBL567975 | 0.70 | ALDH1A1 (0.76) | GAATAS1R3TAS1R1TAS1R2KMT2A | |
| SCHEMBL31287794 | 0.70 | ALDH1A1 (0.76) | GAATAS1R3TAS1R1TAS1R2KMT2A | |
| SCHEMBL23447714 | 0.69 | KMT2A (0.73) | GAAPTGS2PTGS1EGFRFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4690934-A | N-phenylsulfonylisonicotinamide derivatives and their use as fungicides or bactericides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1987-09-01 | — | — | US | disclosed |