Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.60 |
| ▸ | EGFR | P00533 | 4/20 | 0.57 |
| ▸ | FLT1 | P17948 | 5/20 | 0.53 |
| ▸ | FLT4 | P35916 | 5/20 | 0.53 |
| ▸ | KDR | P35968 | 5/20 | 0.53 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.47 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10740984 | 0.86 | PTGS2 (0.55) | PTGS2PTGS1EGFRFLT1FLT4 | |
| SCHEMBL10739775 | 0.86 | ALKBH2 (0.63) | PTGS2PTGS1EGFRFLT1FLT4 | |
| SCHEMBL10745409 | 0.76 | GAA (0.59) | PTGS2PTGS1EGFRFLT1FLT4 | |
| SCHEMBL10621867 | 0.76 | FLT1 (0.54) | PTGS2PTGS1EGFRFLT1FLT4 | |
| SCHEMBL10633305 | 0.73 | LTA4H (0.59) | PTGS1KDR | |
| SCHEMBL28698398 | 0.73 | PTGS2 (0.71) | PTGS2PTGS1EGFRFLT1FLT4 | |
| SCHEMBL10080304 | 0.73 | CES1 (0.55) | — | |
| SCHEMBL10744009 | 0.73 | ALKBH2 (0.51) | PTGS2PTGS1EGFRFLT1FLT4 | |
| SCHEMBL10738335 | 0.72 | ALKBH2 (0.47) | BCL2L1MCL1ALKBH2ALKBH5ALKBH3 | |
| SCHEMBL23447714 | 0.71 | KMT2A (0.73) | PTGS2PTGS1EGFRFLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62161761-A | — | — | None | — | — | JP | disclosed |
| US-4690934-A | N-phenylsulfonylisonicotinamide derivatives and their use as fungicides or bactericides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1987-09-01 | — | — | US | disclosed |
| JP-S62161761-A | N-PHENYLSULFONYLISONICOTINAMIDE DERIVATIVE AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE COMPOSITION CONTAINING SAID DERIVATIVE AS ACTIVE COMPONENT | NIPPON KAYAKU CO LTD | 1987-07-17 | — | — | JP | disclosed |