Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PTGIR | P43119 | 6/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Temefos SCHEMBL44105 | 0.82 | LMNA (0.53) | ALDH1A1LMNACYP3A4HSD17B10SMN1; SMN2 | |
| Temefos SCHEMBL23303378 | 0.82 | LMNA (0.53) | ALDH1A1LMNACYP3A4HSD17B10SMN1; SMN2 | |
| Temefos SCHEMBL8741692 | 0.80 | LMNA (0.51) | ALDH1A1LMNACYP3A4HSD17B10SMN1; SMN2 | |
| Temefos SCHEMBL6388031 | 0.80 | LMNA (0.51) | ALDH1A1LMNACYP3A4HSD17B10SMN1; SMN2 | |
| Temefos SCHEMBL10455340 | 0.76 | LMNA (0.47) | ALDH1A1LMNACYP3A4HSD17B10SMN1; SMN2 | |
| Temefos SCHEMBL15553439 | 0.76 | LMNA (0.51) | ALDH1A1LMNACYP3A4HSD17B10SMN1; SMN2 | |
| Temefos SCHEMBL9435846 | 0.73 | LMNA (0.40) | ALDH1A1LMNACYP3A4HSD17B10SMN1; SMN2 | |
| SCHEMBL30412917 | 0.71 | CYP3A4 (0.53) | ALDH1A1LMNACYP3A4HSD17B10SMN1; SMN2 | |
| Temefos SCHEMBL9193178 | 0.71 | LMNA (0.54) | ALDH1A1LMNACYP3A4HSD17B10SMN1; SMN2 | |
| SCHEMBL11061618 | 0.70 | ALDH1A1 (0.57) | ALDH1A1LMNACYP3A4HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230068-A2 | Use of a geminal diphosphonic acid compound to prepare a medicament | Norwich Eaton Pharmaceuticals, Inc. (US) | 1987-07-29 | — | — | EP | disclosed |