Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Temefos SCHEMBL23303378 | 0.83 | LMNA (0.53) | LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10 | |
| Temefos SCHEMBL44105 | 0.83 | LMNA (0.53) | LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10 | |
| Temefos SCHEMBL6388031 | 0.81 | LMNA (0.51) | LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10 | |
| Temefos SCHEMBL8741692 | 0.81 | LMNA (0.51) | LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10 | |
| Temefos SCHEMBL10455340 | 0.80 | LMNA (0.47) | LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10 | |
| Temefos SCHEMBL15553439 | 0.77 | LMNA (0.51) | LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10 | |
| Temefos SCHEMBL9809762 | 0.77 | LMNA (0.42) | LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10 | |
| Temefos SCHEMBL9193178 | 0.75 | LMNA (0.54) | LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10 | |
| Temefos SCHEMBL20919592 | 0.74 | ALDH1A1 (0.46) | LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10 | |
| Temefos SCHEMBL10748097 | 0.73 | ALDH1A1 (0.39) | LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586521-A1 | CALCIUM, TRACE MINERAL, VITAMIN D AND DRUG THERAPY COMBINATIONS | THE PROCTER & GAMBLE COMPANY (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992021355-A1 | CALCIUM, TRACE MINERAL, VITAMIN D AND DRUG THERAPY COMBINATIONS | THE PROCTER & GAMBLE COMPANY (US) | 1992-12-10 | — | — | WO | disclosed |