Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 2/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PHOSPHO1 | Q8TCT1 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | PMM2 | O15305 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5916533 | 0.88 | KMT2A (0.45) | L3MBTL1G6PDTLR9MAPTALDH1A1 | |
| SCHEMBL10748921 | 0.85 | MAPT (0.37) | L3MBTL1IDO1MAPTTDP1PARP1 | |
| SCHEMBL10502469 | 0.82 | METAP2 (0.59) | G6PDTLR9IDO1MAPTTDP1 | |
| SCHEMBL5916501 | 0.81 | L3MBTL1 (0.40) | L3MBTL1G6PDTLR9MAPTTDP1 | |
| SCHEMBL18770213 | 0.77 | ALDH1A1 (0.41) | L3MBTL1G6PDTLR9MAPTTDP1 | |
| SCHEMBL10745932 | 0.77 | METAP2 (0.45) | G6PDIDO1MAPTTDP1ALDH1A1 | |
| SCHEMBL5916836 | 0.77 | METAP2 (0.49) | G6PDIDO1MAPTTDP1ALDH1A1 | |
| SCHEMBL5916782 | 0.75 | METAP2 (0.61) | G6PDIDO1MAPTTDP1ALDH1A1 | |
| SCHEMBL10502370 | 0.74 | KMT2A (0.42) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL10745708 | 0.74 | TXNRD1 (0.56) | MAPTKAT2BKMT2AMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4711961-A | Benzisoselenazolethiones and process for the treatment of various diseases in humans | A. NATTERMANN & CIE GMBH (DE) | 1987-12-08 | — | — | US | disclosed |
| EP-0154851-A1 | Benzisoselenazolethiones,process for their preparation and pharmaceutical products containing these compounds | A. Nattermann & Cie. GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |