Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14973957 | 0.83 | ALDH1A1 (0.52) | PKMALDH1A1LTA4HKMT2AMAPT | |
| SCHEMBL14973956 | 0.83 | ALDH1A1 (0.51) | PKMALDH1A1LTA4HKMT2ATRPM8 | |
| SCHEMBL10753221 | 0.81 | ALDH1A1 (0.48) | PKMALDH1A1LTA4HKMT2ATRPM8 | |
| SCHEMBL10972161 | 0.77 | USP2 (0.40) | ALDH1A1LTA4HKMT2AMAPT | |
| SCHEMBL14861373 | 0.77 | TDP1 (0.48) | ALDH1A1KMT2ANPSR1 | |
| SCHEMBL10756619 | 0.76 | ALDH1A1 (0.47) | PKMALDH1A1LTA4HKMT2ATRPM8 | |
| SCHEMBL2186007 | 0.76 | CHRNB2 (0.54) | ALDH1A1KMT2ATRPM8HTTSMN1; SMN2 | |
| SCHEMBL10653197 | 0.75 | LTA4H (0.59) | LTA4HTBXAS1MAPT | |
| SCHEMBL6642234 | 0.74 | TBXAS1 (0.60) | LTA4HKMT2ATBXAS1MAPT | |
| SCHEMBL64891 | 0.74 | TBXAS1 (0.59) | ALDH1A1LTA4HTBXAS1NAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4663319-A | LIVER DISORDERS | TANABE SEIYSKU CO., LTD. (JP) | 1987-05-05 | — | — | US | disclosed |
| EP-0149534-A2 | Novel thioketene derivatives and process for the preparation thereof | Tanabe Seiyaku Co., Ltd. (JP) | 1985-07-24 | — | — | EP | disclosed |