Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10752184 | 0.81 | PKM (0.52) | ALDH1A1LTA4HPKMKMT2ATRPM8 | |
| SCHEMBL14973957 | 0.80 | ALDH1A1 (0.52) | ALDH1A1LTA4HPKMKMT2AMAPT | |
| SCHEMBL14973956 | 0.79 | ALDH1A1 (0.51) | ALDH1A1LTA4HPKMKMT2ATRPM8 | |
| SCHEMBL10757422 | 0.79 | ITGB3 (0.37) | ALDH1A1LTA4HLMNAKMT2AMAPT | |
| SCHEMBL10753215 | 0.76 | ALDH1A1 (0.47) | ALDH1A1LMNAPKMKMT2ARIPK1 | |
| SCHEMBL10749977 | 0.76 | MC4R (0.44) | ALDH1A1LMNAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL10752287 | 0.75 | MEN1 (0.44) | LMNAKMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL10752292 | 0.74 | HDAC6 (0.37) | ALDH1A1LMNA | |
| SCHEMBL10756619 | 0.72 | ALDH1A1 (0.47) | ALDH1A1LTA4HLMNAPKMKMT2A | |
| SCHEMBL2186007 | 0.72 | CHRNB2 (0.54) | ALDH1A1RECQLLMNAKMT2ATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4663319-A | LIVER DISORDERS | TANABE SEIYSKU CO., LTD. (JP) | 1987-05-05 | — | — | US | disclosed |