Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PPIB | P23284 | 3/20 | 0.36 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | PPID | Q08752 | 1/20 | 0.36 |
| ▸ | PPIG | Q13427 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10977964 | 0.82 | ALDH1A1 (0.47) | TDP1ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL10757422 | 0.80 | ITGB3 (0.37) | USP2TSHRTDP1HDAC3HDAC1 | |
| SCHEMBL2876660 | 0.78 | TSHR (0.50) | USP2TSHRTDP1HDAC1HDAC6 | |
| SCHEMBL14861373 | 0.78 | TDP1 (0.48) | TSHRTDP1HDAC1HDAC6REN | |
| SCHEMBL10973108 | 0.78 | POLB (0.48) | TSHRALDH1A1MAPT | |
| SCHEMBL10752184 | 0.77 | PKM (0.52) | ALDH1A1KMT2AMAPTLTA4H | |
| SCHEMBL10973111 | 0.76 | HDAC6 (0.39) | TDP1HDAC6RENALDH1A1KDM4E | |
| SCHEMBL16008426 | 0.76 | TSHR (0.48) | USP2TSHRTDP1HDAC1HDAC6 | |
| SCHEMBL13521690 | 0.74 | HDAC3 (0.46) | USP2TSHRHDAC3HDAC1HDAC2 | |
| SCHEMBL71846 | 0.74 | HSD17B10 (0.55) | USP2TSHRHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0149534-A2 | Novel thioketene derivatives and process for the preparation thereof | Tanabe Seiyaku Co., Ltd. (JP) | 1985-07-24 | — | — | EP | disclosed |