Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10756619 | 0.81 | ALDH1A1 (0.47) | ALDH1A1TRPM8MAPTTP53LMNA | |
| SCHEMBL10752178 | 0.76 | LMNA (0.47) | ALDH1A1LMNAPOLBGAAFNTA | |
| SCHEMBL10753215 | 0.73 | ALDH1A1 (0.47) | ALDH1A1LMNAPOLBGAAFNTA | |
| SCHEMBL9621031 | 0.65 | ADRA1A (0.55) | ALDH1A1MAPTLMNAGAAKMT2A | |
| SCHEMBL25438547 | 0.64 | CHRNB2 (0.50) | ALDH1A1LMNAGAARIPK1KMT2A | |
| SCHEMBL27368695 | 0.64 | KMT2A (0.56) | ALDH1A1LMNAPOLBGAAFNTA | |
| SCHEMBL16508902 | 0.64 | TBXAS1 (0.57) | ALDH1A1LMNAPOLBGAANLRP3 | |
| SCHEMBL7863128 | 0.64 | CTDSP1 (0.56) | ALDH1A1TRPM8MAPTLMNAPOLB | |
| SCHEMBL7311226 | 0.63 | LMNA (0.53) | ALDH1A1LMNARIPK1KMT2A | |
| SCHEMBL7311229 | 0.63 | LMNA (0.53) | ALDH1A1LMNARIPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4663319-A | LIVER DISORDERS | TANABE SEIYSKU CO., LTD. (JP) | 1987-05-05 | — | — | US | disclosed |
| EP-0149534-A2 | Novel thioketene derivatives and process for the preparation thereof | Tanabe Seiyaku Co., Ltd. (JP) | 1985-07-24 | — | — | EP | disclosed |