Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 11/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10755802 | 0.84 | THRB (0.36) | LMNAIRAK4 | |
| SCHEMBL10759188 | 0.77 | ITGB1 (0.36) | IRAK4KCNH2 | |
| SCHEMBL3607537 | 0.74 | FDPS (0.46) | LMNAKCNH2 | |
| SCHEMBL10758512 | 0.73 | CYP3A4 (0.46) | DDB1CRBN | |
| SCHEMBL15111283 | 0.73 | CTSD (0.36) | IRAK4KCNH2 | |
| SCHEMBL26030844 | 0.73 | CTSS (0.42) | CTSSCTSK | |
| SCHEMBL23604391 | 0.72 | DRD2 (0.40) | LMNADDB1CRBN | |
| SCHEMBL3733971 | 0.72 | DRD2 (0.40) | LMNADDB1CRBN | |
| SCHEMBL18014831 | 0.72 | IRAK4 (0.38) | LMNADDB1CRBNIRAK4 | |
| SCHEMBL30617431 | 0.71 | DDB1 (0.38) | LMNADDB1CRBNIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4677098-A | REDUCING AMNESIA AND TREATING SENILITY | WARNER-LAMBERT COMPANY (US) | 1987-06-30 | — | — | US | disclosed |
| US-4677114-A | REDUCING AMNESIA, TREATMENT OF SENILITY | WARNER-LAMBERT COMPANY (US) | 1987-06-30 | — | — | US | disclosed |