SCHEMBL107623

SCHEMBL107623

C#Cc1ccc(C(=O)Cl)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
CA12 O43570 1/20 0.40
CA4 P22748 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
PTPN1 P18031 1/20 0.38
HDAC8 Q9BY41 2/20 0.37
AKR1C3 P42330 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
CYP2C9 P11712 1/20 0.34
CTSL P07711 1/20 0.34
CTSB P07858 1/20 0.34
CTSS P25774 1/20 0.34
DRD2 P14416 1/20 0.33
DRD4 P21917 1/20 0.33
DRD3 P35462 1/20 0.33
USP4 Q13107 1/20 0.33
USP7 Q93009 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3838955 0.80 SRD5A2 (0.48) ALDH1A1CA1CA2CA12CA4
SCHEMBL13582530 0.80 CES2 (0.48) CA1CA2CA12CA4CA9
SCHEMBL19554327 0.80 CES2 (0.38) ALDH1A1PTPN1HDAC6
SCHEMBL68148 0.79 ALDH1A1 (0.59) ALDH1A1CA1CA2CA12CA4
SCHEMBL20587670 0.79 ALDH1A1 (0.59) ALDH1A1CA1CA2CA12CA4
SCHEMBL40299 0.78 TSHR (0.60) ALDH1A1CA1CA2CA12CA4
SCHEMBL10938155 0.78 CA1 (0.41) CA1CA2CA12CA4CA9
SCHEMBL16994931 0.78 CA1 (0.41) CA1CA2CA12CA4CA9
SCHEMBL101544 0.78 ALDH1A1 (0.45) ALDH1A1CA1CA2
SCHEMBL23390996 0.76 PTPN1 (0.42) CA1CA2CA12CA4CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112831059-B Modified lignin, preparation method thereof and application thereof in rubber composite material 南京工业大学 2021-11-26 CN claimed
CN-112831059-A Modified lignin, preparation method thereof and application thereof in rubber composite material 南京工业大学 2021-05-25 CN claimed
US-10308749-B2 Process for producing modified thermosetting polyphenylene ether resin NAN YA PLASTICS CORPORATION (TW) 2019-06-04 US claimed
US-20180051116-A1 PROCESS FOR PRODUCING MODIFIED THERMOSETTING POLYPHENYLENE ETHER RESIN NAN YA PLASTICS CORPORATION (TW) 2018-02-22 US claimed
US-4638083-A ESTERIFICATION OF HYDROXY COMPOUND WITH ETHYNYL BENZOYL CHLORIDE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS & SPACE ADMINISTRATION (US) 1987-01-20 US claimed
US-4567240-A Ethynyl terminated ester oligomers and polymers therefrom THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1986-01-28 US claimed
US-4565886-A CHLORINATING AN ACETYLENE-SUBSTITUTED BENZOIC ACID BY THIONYL CHLORIDE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1986-01-21 US claimed
US-4510296-A FOR COATINGS AND MOLDING; SOLVENT RESISTANCE HIGH USE TEMPERATURE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1985-04-09 US claimed
US-4431761-A CROSSLINKABLE THERMOPLASTIC RESINS; SOLVENT AND HEAT RESISTANCE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1984-02-14 US claimed
US-20260139272-A1 LACTAM-MODIFIED ADENO-ASSOCIATED VIRUS VECTORS COAVE THERAPEUTICS (FR) 2026-05-21 US disclosed
US-20260079401-A1 COMPOSITION AND METHOD FOR MANUFACTURING SEMICONDUCTOR SUBSTRATE JSR CORPORATION (JP) 2026-03-19 US disclosed
US-12545929-B2 Lactam-modified adeno-associated virus vectors COAVE THERAPEUTICS (FR) 2026-02-10 US disclosed
EP-4240837-B1 LACTAM-MODIFIED ADENO-ASSOCIATED VIRUS VECTORS COAVE THERAPEUTICS (FR) 2026-01-28 EP disclosed
US-20250257041-A1 INDUCERS OF INTEGRATED STRESS RESPONSE TO TREAT CANCER THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2025-08-14 US disclosed
US-4560699-A ANTIPYRETICS, ANTICOAGULANTS, VASODILAAORS, MUSCLE RELAXANTS SYNTEX (U.S.A.) INC. (US) 1985-12-24 US disclosed
US-4510296-A FOR COATINGS AND MOLDING; SOLVENT RESISTANCE HIGH USE TEMPERATURE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1985-04-09 US disclosed
EP-0114632-A1 5-(4-Vinyl- or 4-ethynylbenzoyl)-1,2-dihydro-3H-pyrrolo-(1,2-A)-pyrrole-1-carboxylic acids and derivatives thereof SYNTEX (U.S.A.) INC. (US) 1984-08-01 EP disclosed
US-4431761-A CROSSLINKABLE THERMOPLASTIC RESINS; SOLVENT AND HEAT RESISTANCE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1984-02-14 US disclosed
US-4431761-A CROSSLINKABLE THERMOPLASTIC RESINS; SOLVENT AND HEAT RESISTANCE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1984-02-14 US disclosed
US-4004025-A Long-acting local subcutaneously-applied anesthetics and compositions containing the same Lewenstein, Evalina (US) 1977-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260079401-A1 COMPOSITION AND METHOD FOR MANUFACTURING SEMICONDUCTOR SUBSTRATE SEM1, RER1, GAR1 ALDH1A1 1723/4885CA1 664/4885CA2 1781/4885
US-20250257041-A1 INDUCERS OF INTEGRATED STRESS RESPONSE TO TREAT CANCER DDIT3, ATF4, EIF2AK3 ALDH1A1 4205/4885CA1 4658/4885CA2 4199/4885
US-12545929-B2 Lactam-modified adeno-associated virus vectors ITGAV, HAVCR2, LDLR ALDH1A1 365/4885CA1 1155/4885CA2 1506/4885
US-20260139272-A1 LACTAM-MODIFIED ADENO-ASSOCIATED VIRUS VECTORS OXA1L, ARCN1, ACTN1 ALDH1A1 337/4885CA1 1202/4885CA2 2054/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.