Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16290014 | 0.78 | L3MBTL1 (0.39) | CYP2A6CYP2B6 | |
| SCHEMBL10754125 | 0.76 | ALDH1A1 (0.41) | CYP2A6CYP2B6 | |
| SCHEMBL23569069 | 0.73 | KDM4E (0.30) | — | |
| SCHEMBL17192 | 0.71 | — | — | |
| SCHEMBL4068463 | 0.71 | TRPV4 (0.47) | TRPV4 | |
| SCHEMBL27456780 | 0.70 | PTGS2 (0.38) | CYP2A6 | |
| SCHEMBL10756361 | 0.69 | — | — | |
| SCHEMBL4064709 | 0.67 | TRPV4 (0.46) | TRPV4 | |
| SCHEMBL9339232 | 0.67 | RAPGEF4 (0.41) | TRPV4 | |
| SCHEMBL23531734 | 0.67 | TRPV4 (0.35) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021123237-A1 | 2-AMINO-N-(AMINO-OXO-ARYL-LAMBDA6-SULFANYLIDENE)ACETAMIDE COMPOUNDS AND THEIR THERAPEUTIC USE | Oxford Drug Design Limited (GB) | 2021-06-24 | — | — | WO | disclosed |
| US-4645529-A | POSTEMERGENCE AND PREEMERGENCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-02-24 | — | — | US | disclosed |
| US-4523943-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-06-18 | — | — | US | disclosed |
| EP-0041404-B1 | HERBICIDAL THIOPHENESULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-01-30 | — | — | EP | disclosed |
| US-4398939-A | Herbicidal thiophenesulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-08-16 | — | — | US | disclosed |
| EP-0041404-A2 | Herbicidal thiophenesulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-12-09 | — | — | EP | disclosed |
| US-4237130-A | DIURETICS, HYPOTENSIVE AGENTS | MERCK & CO., INC. (US) | 1980-12-02 | — | — | US | disclosed |