Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8130850 | 0.95 | CYP3A4 (0.43) | CYP3A4TSHRMAPK1ALDH1A1PKM | |
| SCHEMBL8579882 | 0.84 | CYP3A4 (0.38) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 | |
| Dimethylamine SCHEMBL10776405 | 0.79 | ALDH1A1 (0.41) | CYP3A4TSHRALDH1A1CYP1A2ALOX15 | |
| SCHEMBL10492874 | 0.78 | TDP1 (0.39) | CYP3A4ALDH1A1ALOX15TDP1MEN1 | |
| SCHEMBL10478429 | 0.75 | APAF1 (0.44) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 | |
| Dimethylamine SCHEMBL10753821 | 0.74 | ACP3 (0.47) | CYP3A4TSHRALDH1A1CYP1A2ALOX15 | |
| SCHEMBL25998080 | 0.73 | ALDH1A1 (0.35) | CYP3A4TSHRMAPK1ALDH1A1PKM | |
| SCHEMBL22044344 | 0.73 | ALDH1A1 (0.45) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL5612635 | 0.73 | ALDH1A1 (0.45) | CYP3A4MAPK1ALDH1A1PKMCYP1A2 | |
| SCHEMBL8389678 | 0.72 | EPHX1 (0.41) | CYP3A4TSHRMAPK1CYP2C9HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115198-B1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTIVE ELEMENTS | TOMOEGAWA PAPER MANUFACTURING COMPANY LIMITED (JP) | 1987-03-11 | — | — | EP | disclosed |
| US-4539282-A | SENSITIZED ZINC OXIDE, POLYCARBONATE BINDER AND AROMATIC DIAMINE | TOMOEGAWA PAPER MANUFACTURING COMPANY LIMITED (JP) | 1985-09-03 | — | — | US | disclosed |
| EP-0115198-A1 | Electrophotographic photoconductive elements | TOMOEGAWA PAPER MANUFACTURING COMPANY LIMITED (JP) | 1984-08-08 | — | — | EP | disclosed |