Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8130850 | 0.76 | CYP3A4 (0.43) | CYP2C9TSHRCYP3A4MAPK1 | |
| SCHEMBL10478429 | 0.74 | APAF1 (0.44) | TSHRCYP3A4MAPK1 | |
| Dimethylamine SCHEMBL10775328 | 0.72 | CYP3A4 (0.39) | CYP2C9TSHRHTR2ACYP3A4MAPK1 | |
| SCHEMBL11511762 | 0.72 | SKP2 (0.53) | EPHX1PTGS1PTGS2CXCR1CXCR2 | |
| SCHEMBL19840416 | 0.67 | CYP3A4 (0.55) | LMNATSHRCYP3A4MAPK1 | |
| SCHEMBL10492808 | 0.67 | MEN1 (0.43) | PTGS1PTGS2ALOX5AKR1C3TSHR | |
| SCHEMBL19806863 | 0.67 | ESR1 (0.47) | EPHX1PTGS1PTGS2CXCR1CXCR2 | |
| SCHEMBL10492799 | 0.67 | EPHX1 (0.42) | EPHX1PTGS1PTGS2CXCR1CXCR2 | |
| SCHEMBL6572888 | 0.66 | ALDH1A1 (0.61) | TSHRCYP3A4MAPK1 | |
| SCHEMBL1131597 | 0.66 | PTGS1 (0.56) | EPHX1PTGS1PTGS2CXCR1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614934-B1 | Colored resin, colored molded resin member and color filter | ORIENT CHEMICAL IND (JP) | 1999-04-28 | — | — | EP | disclosed |
| US-5869509-A | TREAT DISORDERS RESPONSIVE TO OPENERS OF THE LARGE CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-02-09 | — | — | US | disclosed |
| EP-0490253-B1 | Magenta toner for developing electrostatic images | ORIENT CHEMICAL IND (JP) | 1996-03-06 | — | — | EP | disclosed |
| EP-0614934-A1 | Colored resin, colored molded resin member and color filter | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1994-09-14 | — | — | EP | disclosed |
| US-5254420-A | Disazo dye | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-19 | — | — | US | disclosed |
| EP-0490253-A2 | Magenta toner for developing electrostatic images | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1992-06-17 | — | — | EP | disclosed |