Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.59 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.48 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
| ▸ | FURIN | P09958 | 7/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | NMT2 | O60551 | 1/20 | 0.42 |
| ▸ | NMT1 | P30419 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | GNPAT | O15228 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10864620 | 0.85 | NOD1 (0.53) | NOD1FOLH1SLC6A5ESR1PGR | |
| SCHEMBL29430995 | 0.83 | NOD1 (0.51) | NOD1SLC6A5ESR1PGRHTR1A | |
| SCHEMBL6129561 | 0.83 | NOD1 (0.61) | NOD1FOLH1SLC6A5FURINNMT2 | |
| SCHEMBL2508780 | 0.83 | NOD1 (0.61) | NOD1FOLH1SLC6A5FURINNMT2 | |
| SCHEMBL21330513 | 0.81 | NOD1 (0.68) | NOD1FOLH1SLC6A5NMT2NMT1 | |
| SCHEMBL19529151 | 0.81 | NOD1 (0.68) | NOD1FOLH1SLC6A5NMT2NMT1 | |
| SCHEMBL29398096 | 0.81 | GNPAT (0.53) | FOLH1FURINGNPAT | |
| SCHEMBL22607329 | 0.81 | SIRT5 (0.54) | NOD1FOLH1ESR1PGRHTR1A | |
| SCHEMBL29527293 | 0.80 | NOD1 (0.58) | NOD1FOLH1SLC6A5FURINNMT2 | |
| SCHEMBL1573989 | 0.80 | NOD1 (0.58) | NOD1FOLH1SLC6A5FURINNMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0149581-B1 | COMPOSITIONS CONTAINING OLIGO-MURAMYLPEPTIDES AND THEIR APPLICATION, IN PARTICULAR FOR THE ACTIVATION OF MACROPHAGES | ANVAR Agence Nationale de Valorisation de la Recherche (FR) | 1987-07-22 | — | — | EP | disclosed |
| EP-0149581-A2 | Compositions containing oligo-muramylpeptides and their application, in particular for the activation of macrophages | ANVAR Agence Nationale de Valorisation de la Recherche (FR) | 1985-07-24 | — | — | EP | disclosed |