Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.39 |
| ▸ | NMT2 | O60551 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7513545 | 0.89 | FOLH1 (0.46) | FOLH1ITGB3ITGA2B | |
| SCHEMBL11120073 | 0.86 | NOD1 (0.46) | NOD1RENACE | |
| SCHEMBL10778212 | 0.85 | NOD1 (0.59) | NOD1FOLH1SLC6A5ESR1PGR | |
| SCHEMBL9224622 | 0.81 | KMT2A (0.43) | REN | |
| SCHEMBL28501207 | 0.81 | REN (0.47) | FOLH1RENACE | |
| SCHEMBL18953127 | 0.81 | KMT2A (0.43) | REN | |
| SCHEMBL18953129 | 0.81 | KMT2A (0.43) | REN | |
| SCHEMBL10788830 | 0.81 | REN (0.47) | FOLH1RENACE | |
| SCHEMBL28501209 | 0.81 | REN (0.47) | FOLH1RENACE | |
| SCHEMBL7782848 | 0.79 | CTSK (0.49) | RENITGB3ITGA2BTLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0173960-A2 | Muramylpeptide active ester derivatives | Hamaoka, Toshiyuki (JP) | 1986-03-12 | — | — | EP | disclosed |