Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4189734 | 0.82 | ALDH1A1 (0.34) | ALDH1A1MAPT | |
| SCHEMBL4189737 | 0.82 | ALDH1A1 (0.34) | ALDH1A1MAPT | |
| SCHEMBL6546547 | 0.75 | CYP2C19 (0.35) | ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL476117 | 0.74 | CES2 (0.38) | ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL9156477 | 0.74 | SMYD2 (0.41) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7599259 | 0.72 | ALDH1A1 (0.36) | ALDH1A1MAPT | |
| SCHEMBL6545076 | 0.72 | KDM4E (0.36) | ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL12921004 | 0.71 | SMYD2 (0.42) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6072557 | 0.71 | ABL1 (0.35) | MAPTSMN1; SMN2 | |
| SCHEMBL6656947 | 0.71 | NR4A2 (0.38) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244364-A2 | Preparation of olefinic compounds | SANDOZ AG (CH) | 1987-11-04 | — | — | EP | disclosed |