Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 17/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL951472 | 0.84 | ALKBH5 (0.73) | ALKBH5ALDH1A1MAPT | |
| SCHEMBL11774629 | 0.83 | ALKBH5 (0.71) | ALKBH5KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL9505312 | 0.83 | ALKBH5 (1.00) | ALKBH5KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL6807273 | 0.83 | ALKBH5 (0.69) | ALKBH5KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL1265504 | 0.80 | ALKBH5 (0.67) | ALKBH5KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL1266522 | 0.80 | ALKBH5 (0.66) | ALKBH5KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL67421 | 0.80 | ALKBH5 (0.66) | ALKBH5KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL692998 | 0.78 | ALKBH5 (0.64) | ALKBH5KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL7883066 | 0.78 | ALKBH5 (0.64) | ALKBH5KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL10755227 | 0.78 | ALDH1A1 (0.57) | ALKBH5KDM4EALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4677199-A | Reactive dyes containing substituted 4-fluoropyridaz-6-one radicals | BASF AKTIENGESELLSCHAFT (DE) | 1987-06-30 | — | — | US | disclosed |
| EP-0106080-B1 | HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC AGENTS CONTAINING THESE COMPOUNDS | LUDWIG HEUMANN & CO GMBH (DE) | 1987-01-28 | — | — | EP | disclosed |
| EP-0082415-B1 | HEAVY METAL COMPLEX AZO COMPOUNDS SOLUBLE IN WATER, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-04-30 | — | — | EP | disclosed |
| US-4556707-A | DYEING CELLULOSE FIBERS AND POLYAMIDE FIBERS | BAYER AKTIENGESELLSCHAFT (DE) | 1985-12-03 | — | — | US | disclosed |
| US-4540776-A | Reactive fluorotriazinylaminonaphthotriazolyphenylazopyridone or pyrimidone dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1985-09-10 | — | — | US | disclosed |
| EP-0106080-A1 | Heterocyclic compounds, process for their preparation and therapeutic agents containing these compounds | LUDWIG HEUMANN & CO GMBH (DE) | 1984-04-25 | — | — | EP | disclosed |
| US-4409142-A | LEATHER | SANDOZ LTD. (CH) | 1983-10-11 | — | — | US | disclosed |
| EP-0083765-A2 | Reactive dyes | BASF Aktiengesellschaft (DE) | 1983-07-20 | — | — | EP | disclosed |
| EP-0082415-A1 | Heavy metal complex azo compounds soluble in water, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-06-29 | — | — | EP | disclosed |
| EP-0078008-A2 | Reactive dyestuffs | BASF Aktiengesellschaft (DE) | 1983-05-04 | — | — | EP | disclosed |
| US-4374064-A | Metal complexes of disazo compounds having a 5-amino or hydroxy-3-carboxy or methyl-1- substituted phenylpyrazole coupling component radical | SANDOZ LTD. (CH) | 1983-02-15 | — | — | US | disclosed |
| US-4354968-A | Azo reactive dyestuffs having an aryl-triazinyl-aryl diazo component | BAYER AKTIENGESELLSCHAFT (DE) | 1982-10-19 | — | — | US | disclosed |
| US-4261889-A | TRIAZINE DYES FOR COTTON | CIBA-GEIGY CORP. (US) | 1981-04-14 | — | — | US | disclosed |
| US-4225492-A | Water-soluble disazo dyestuffs, prepared from unsymmetrical heterocyclic diamines | CASSELLA AKTIENGESELLSCHAFT (DE) | 1980-09-30 | — | — | US | disclosed |
| US-4145340-A | WATER-SOLUBLE REACTIVE MONOAZO DYE CONTAINING A NONYLPHENOXY, CHLOROTRIAZINE GROUP | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-03-20 | — | — | US | disclosed |