Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10356117 | 0.81 | MAOB (0.38) | MAOBMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL10879067 | 0.77 | FAAH (0.46) | MAOBKDM4EALDH1A1POLB | |
| SCHEMBL10877406 | 0.76 | FAAH (0.50) | MAOBMRGPRX4ALDH1A1POLB | |
| Flumecinol SCHEMBL667363 | 0.76 | ALDH1A1 (0.45) | MAPTHTTL3MBTL1ALDH1A1POLB | |
| SCHEMBL10783493 | 0.76 | NR4A2 (0.55) | MAOBFFAR1FFAR4NR4A2MAPT | |
| SCHEMBL10784574 | 0.75 | IDH1 (0.52) | MAOBNR4A2MAPTKDM4EALDH1A1 | |
| SCHEMBL10881215 | 0.75 | FAAH (0.44) | MAOBKDM4EALDH1A1POLB | |
| SCHEMBL10740804 | 0.75 | ESR1 (0.47) | MAPTHTTKDM4EALDH1A1POLB | |
| SCHEMBL10356364 | 0.74 | TRPM8 (0.55) | MAOBNR4A2MAPTKDM4EALDH1A1 | |
| SCHEMBL10877636 | 0.74 | ALDH1A1 (0.51) | ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116787-B1 | 1,1-DIPHENYLPROPANOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1987-03-18 | — | — | EP | disclosed |
| EP-0116787-A1 | 1,1-Diphenylpropanol derivatives, process for their preparation and pharmaceutical compositions containing them | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1984-08-29 | — | — | EP | disclosed |