Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 2/20 | 0.47 |
| ▸ | FLT4 | P35916 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14310501 | 0.83 | FLT1 (0.46) | FLT1FLT4KDRCYP11B2SMN1; SMN2 | |
| SCHEMBL12532565 | 0.82 | SMN1; SMN2 (0.59) | FLT1FLT4KDRNR1H4SMN1; SMN2 | |
| SCHEMBL107882 | 0.82 | FLT1 (0.51) | FLT1FLT4KDRCYP11B2SMN1; SMN2 | |
| SCHEMBL11988898 | 0.80 | NFE2L2 (0.45) | FLT1FLT4KDRSMN1; SMN2NPC1 | |
| SCHEMBL250256 | 0.79 | FLT1 (0.53) | FLT1FLT4KDRCYP11B2SMN1; SMN2 | |
| SCHEMBL10917039 | 0.79 | ABL1 (0.59) | FLT1FLT4KDRSMN1; SMN2RAB9A | |
| SCHEMBL13900904 | 0.79 | CYP11B2 (0.45) | FLT1FLT4KDRCYP11B2SMN1; SMN2 | |
| SCHEMBL11988942 | 0.78 | ESRRB (0.49) | SMN1; SMN2NPC1RAB9ATSHRHTT | |
| SCHEMBL28019535 | 0.78 | KDM4E (0.53) | SMN1; SMN2RAB9ATSHRCASP1MYC | |
| SCHEMBL109654 | 0.78 | SMN1; SMN2 (0.63) | FLT1FLT4KDRSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257382-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257382-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | TRPC5, TRPC1, GOT1 | FLT1 4461/4885FLT4 4610/4885KDR 4104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.