Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.72 |
| ▸ | CTSB | P07858 | 4/20 | 0.72 |
| ▸ | CTSS | P25774 | 4/20 | 0.72 |
| ▸ | CTSK | P43235 | 1/20 | 0.72 |
| ▸ | TACR1 | P25103 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13220863 | 1.00 | CTSL (0.72) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL11516887 | 0.92 | CTSS (0.62) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL6661701 | 0.90 | CTSL (0.69) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL10790294 | 0.90 | CTSL (0.69) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL9557048 | 0.88 | CTSL (0.73) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL7314524 | 0.88 | CTSL (0.73) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL24115146 | 0.88 | CTSK (0.73) | CTSLCTSBCTSSCTSK | |
| SCHEMBL20669315 | 0.88 | CTSK (0.73) | CTSLCTSBCTSSCTSK | |
| SCHEMBL8335400 | 0.87 | CTSL (0.71) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL5177047 | 0.87 | CTSS (0.56) | CTSLCTSBCTSSCTSKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1180115-A1 | MINIMAL ISOLATION PEPTIDE SYNTHESIS PROCESS USING ION-EXCHANGE RESINS AS SCAVENGING AGENTS | ABBOTT LABORATORIES (US) | 2002-02-20 | — | — | EP | disclosed |
| WO-2000071569-A1 | MINIMAL ISOLATION PEPTIDE SYNTHESIS PROCESS USING ION-EXCHANGE RESINS AS SCAVENGING AGENTS | ABBOTT LABORATORIES (US) | 2000-11-30 | — | — | WO | disclosed |
| EP-0248562-B1 | Difluoro peptide compounds | ZENECA INC (US) | 1995-10-25 | — | — | EP | disclosed |
| US-4873221-A | Difluoro peptide compounds | ICI AMERICAS INC. (US) | 1989-10-10 | — | — | US | disclosed |
| EP-0248562-A2 | Difluoro peptide compounds | ZENECA INC. (US) | 1987-12-09 | — | — | EP | disclosed |