Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 2/20 | 0.39 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | FABP2 | P12104 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29029147 | 0.75 | CLCN2 (0.53) | CLCN2KMT2AMEN1MAPTAKR1C2 | |
| SCHEMBL7642234 | 0.75 | PTGS1 (0.46) | KMT2APTGS1MEN1PTGS2LMNA | |
| SCHEMBL10871117 | 0.73 | KMT2A (0.49) | KMT2AMEN1LMNAMAPTHPGD | |
| SCHEMBL7684364 | 0.72 | CLCN2 (0.47) | CLCN2KMT2AMEN1LMNACYP2C9 | |
| Metbufen SCHEMBL2111106 | 0.69 | SMN1; SMN2 (0.59) | PTGS2LMNAMAPTHPGDTSHR | |
| SCHEMBL135355 | 0.68 | L3MBTL1 (0.66) | KMT2AMEN1LMNAMAPTHPGD | |
| SCHEMBL10788896 | 0.68 | STING1 (0.40) | STING1KMT2AMEN1LMNAMAPT | |
| SCHEMBL3671148 | 0.67 | KMO (0.69) | STING1HPGDTSHR | |
| SCHEMBL1768168 | 0.67 | AKR1C3 (0.53) | KMT2APTGS1MEN1PTGS2LMNA | |
| SCHEMBL3671146 | 0.67 | KMO (0.69) | STING1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0180290-B1 | OMEGA-(2',4'-DIHALOBIPHENYLYL)OXO ALKANOIC ACIDS AND PROCESS FOR THEIR PREPARATION | SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu (CS) | 1987-10-28 | — | — | EP | claimed |