Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | PLK1 | P53350 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.59 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ELANE | P08246 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845256 | 0.95 | L3MBTL1 (0.77) | L3MBTL1LMNAMAPK1KMT2ANPSR1 | |
| SCHEMBL845348 | 0.87 | NPSR1 (0.79) | L3MBTL1LMNAMAPK1KMT2ANPSR1 | |
| SCHEMBL7635359 | 0.84 | NPC1 (0.64) | L3MBTL1LMNAMAPK1KMT2APLK1 | |
| SCHEMBL11750725 | 0.84 | L3MBTL1 (0.63) | L3MBTL1LMNAMAPK1KMT2ANPSR1 | |
| SCHEMBL460957 | 0.84 | CES2 (0.63) | L3MBTL1LMNAMAPK1KMT2ANPSR1 | |
| SCHEMBL11755151 | 0.83 | LMNA (0.67) | L3MBTL1LMNAMAPK1KMT2ANPSR1 | |
| SCHEMBL31527717 | 0.83 | LMNA (0.67) | L3MBTL1LMNAMAPK1KMT2ANPSR1 | |
| SCHEMBL28912681 | 0.83 | PLK1 (0.72) | L3MBTL1LMNAMAPK1KMT2ANPSR1 | |
| SCHEMBL11003334 | 0.81 | LMNA (0.78) | L3MBTL1LMNAMAPK1KMT2ANPSR1 | |
| SCHEMBL11750720 | 0.81 | KMT2A (0.60) | L3MBTL1LMNAMAPK1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168175-B1 | PREPARATION OF TAMOXIFEN | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-11-19 | — | — | EP | disclosed |
| EP-0168175-A1 | Preparation of tamoxifen | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-01-15 | — | — | EP | disclosed |