SCHEMBL1081012

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1007810	0.89	SLC22A12 (0.58)	SLC22A12PPARGPPARASMN1; SMN2MEN1
	SCHEMBL1584780	0.86	SLC22A12 (0.55)	SLC22A12L3MBTL1NPC1PKMNFKB1
	SCHEMBL1584983	0.85	SLC22A12 (0.54)	SLC22A12SMN1; SMN2MEN1KMT2AALDH1A1
	SCHEMBL460443	0.85	SLC22A12 (1.00)	SLC22A12NFKB1RXRARXRBRXRG
	SCHEMBL1010327	0.83	SLC22A12 (0.50)	SLC22A12PPARGPPARAL3MBTL1TSHR
	SCHEMBL3094003	0.82	SLC22A12 (0.49)	SLC22A12PPARGPPARAL3MBTL1SMN1; SMN2
	SCHEMBL18297332	0.79	DRD2 (0.53)	SLC22A12L3MBTL1NPC1PKMNFKB1
	SCHEMBL31594790	0.79	ALDH1A1 (0.49)	L3MBTL1NPC1PKMNFKB1RAB9A
	SCHEMBL1008089	0.79	ALDH1A1 (0.49)	L3MBTL1NPC1PKMNFKB1RAB9A
	SCHEMBL1008570	0.78	TBXAS1 (0.51)	SLC22A12PPARGPPARAL3MBTL1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.