Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1010327 | 0.86 | SLC22A12 (0.50) | SLC22A12PPARGPPARATSHRMAOB | |
| SCHEMBL954556 | 0.84 | SLC22A12 (0.68) | SLC22A12ALOX5NR1H4 | |
| SCHEMBL1203178 | 0.82 | ALOX5 (0.67) | ALDH1A1ALOX5MAOBL3MBTL1NR1H4 | |
| SCHEMBL1081012 | 0.82 | SLC22A12 (0.74) | SLC22A12ALDH1A1HPGDPPARGPPARA | |
| SCHEMBL181473 | 0.81 | HPGD (0.61) | TBXAS1ALDH1A1HPGDCYP4Z1SMN1; SMN2 | |
| SCHEMBL10562538 | 0.81 | ALDH1A1 (0.43) | TBXAS1ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL6904947 | 0.80 | TBXAS1 (0.53) | TBXAS1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL10564801 | 0.80 | MAOB (0.44) | TBXAS1ALDH1A1HPGDTSHRKMT2A | |
| SCHEMBL2087071 | 0.80 | NPC1 (0.49) | ALDH1A1MAOBATMTDP1L3MBTL1 | |
| SCHEMBL1007810 | 0.79 | SLC22A12 (0.58) | SLC22A12ALDH1A1HPGDPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234464-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | WELLSTAT THERAPEUTICS CORPORATION (US) | 2010-09-16 | — | — | US | disclosed |
| EP-2026659-A2 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | Wellstat Therapeutics Corporation (US) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007146768-A2 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | WELLSTAT THERAPEUTICS CORPORATION (US) | 2007-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234464-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PC, GOT2, OAT | SLC22A12 1715/4885TBXAS1 585/4885ALDH1A1 1793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.