Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.34 |
| ▸ | TK1 | P04183 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10816686 | 0.83 | L3MBTL1 (0.43) | ALDH1A1MAPK14TSHREGLN1ALKBH1 | |
| SCHEMBL10811050 | 0.72 | EGLN1 (0.43) | MAPK14EGLN1MAOBALKBH1RAB9A | |
| SCHEMBL10742364 | 0.70 | CYP1A2 (0.43) | ALDH1A1TSHRRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10733734 | 0.70 | SMN1; SMN2 (0.48) | RAB9ASMN1; SMN2NPC1L3MBTL1MKNK1 | |
| SCHEMBL10816545 | 0.69 | EGLN1 (0.41) | MAPK14EGLN1MAOBALKBH1RAB9A | |
| SCHEMBL10814782 | 0.69 | EGLN1 (0.41) | MAPK14EGLN1MAOBALKBH1PKM | |
| SCHEMBL10811918 | 0.69 | EGLN1 (0.39) | EGLN1ALKBH1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11018085 | 0.69 | RXRA (0.41) | ALDH1A1TSHREGLN1PKMRAB9A | |
| SCHEMBL10815000 | 0.68 | RXRA (0.46) | ALDH1A1EGLN1MAOBALKBH1RAB9A | |
| SCHEMBL5828559 | 0.67 | ALDH1A1 (0.49) | ALDH1A1MAPK14TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0087326-B1 | SUBSTITUTED PYRIMIDIN-2-ONES AND THE SALTS THEREOF | NYCOMED AS (NO) | 1987-05-13 | — | — | EP | disclosed |
| US-4539324-A | ANTICANCER AGENTS | NYEGAARD & CO. A/S (NO) | 1985-09-03 | — | — | US | disclosed |
| EP-0087326-A1 | Substituted pyrimidin-2-ones and the salts thereof | NYCOMED AS (NO) | 1983-08-31 | — | — | EP | disclosed |