Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | RGS12 | O14924 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | PLA2G2A | P14555 | 11/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10526172 | 0.88 | PTGS2 (0.62) | LMNACYP1A2CYP2C9PMP22MEN1 | |
| SCHEMBL10526127 | 0.85 | PTGS2 (0.60) | LMNACYP1A2CYP2C9PMP22MEN1 | |
| SCHEMBL10527799 | 0.83 | PTGS2 (0.64) | LMNACYP1A2CYP2C9PMP22MEN1 | |
| SCHEMBL10525264 | 0.77 | PTGS2 (0.56) | LMNACYP1A2CYP2C9PMP22MEN1 | |
| SCHEMBL10524337 | 0.76 | PTGS2 (0.69) | LMNACYP1A2CYP2C9PMP22MEN1 | |
| SCHEMBL10524488 | 0.76 | PTGS2 (0.54) | PTGS2 | |
| SCHEMBL10523837 | 0.76 | PTGS2 (0.59) | LMNACYP1A2CYP2C9PMP22MEN1 | |
| SCHEMBL10817893 | 0.75 | LMNA (0.49) | TSHRLMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9184235 | 0.75 | PTGS2 (0.52) | TSHRLMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1322507 | 0.74 | LMNA (1.00) | TSHRLMNACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4696929-A | Derivative of piperazine having anti-allergic and anti-inflammatory action | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1987-09-29 | — | — | US | disclosed |