Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10818396 | 0.88 | L3MBTL1 (0.38) | L3MBTL1TDP1ATMBCHEADRB2 | |
| SCHEMBL11187728 | 0.78 | LMNA (0.40) | BCHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL10969158 | 0.74 | ALOX5 (0.44) | L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL11422568 | 0.74 | IDO1 (0.48) | CHRNB2CHRNB4CHRNA3CHRNA4ALOX5 | |
| SCHEMBL11277037 | 0.73 | ALDH1A1 (0.49) | L3MBTL1TDP1 | |
| SCHEMBL27726032 | 0.71 | TDP1 (0.49) | L3MBTL1TDP1ATMBCHEADRB2 | |
| SCHEMBL30605965 | 0.71 | TDP1 (0.49) | L3MBTL1TDP1ATMBCHEADRB2 | |
| SCHEMBL17502798 | 0.71 | TDP1 (0.49) | L3MBTL1TDP1ATMBCHEADRB2 | |
| SCHEMBL3939804 | 0.71 | TDP1 (0.49) | L3MBTL1TDP1ATMBCHEADRB2 | |
| SCHEMBL965339 | 0.71 | TDP1 (0.47) | L3MBTL1TDP1ATMBCHEPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0084948-B1 | PENICILLIN DERIVATIVES | BEECHAM GROUP PLC (GB) | 1987-11-04 | — | — | EP | disclosed |
| US-4455314-A | Penicillin derivatives | BEECHAM GROUP P.L.C. (GB) | 1984-06-19 | — | — | US | disclosed |
| EP-0084948-A1 | Penicillin derivatives | BEECHAM GROUP PLC (GB) | 1983-08-03 | — | — | EP | disclosed |