Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10815737 | 0.88 | L3MBTL1 (0.36) | L3MBTL1TDP1ATMPPARGBCHE | |
| SCHEMBL10492974 | 0.81 | ATM (0.43) | L3MBTL1TDP1ATMIDO1TDO2 | |
| SCHEMBL10650923 | 0.74 | IDO1 (0.50) | IDO1TDO2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL11260231 | 0.74 | LMNA (0.41) | IDO1TDO2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL162736 | 0.74 | SRC (0.50) | L3MBTL1IDO1TDO2CHRNB2CHRNB4 | |
| SCHEMBL11101690 | 0.73 | ALDH1A1 (0.44) | L3MBTL1TDP1 | |
| SCHEMBL11664079 | 0.73 | SRC (0.48) | L3MBTL1ATMIDO1TDO2SRC | |
| SCHEMBL10918696 | 0.72 | SRC (0.48) | IDO1TDO2CHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL11244144 | 0.72 | SRC (0.48) | IDO1TDO2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3632860 | 0.70 | TDP1 (0.44) | L3MBTL1TDP1ATMPPARGBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0084948-B1 | PENICILLIN DERIVATIVES | BEECHAM GROUP PLC (GB) | 1987-11-04 | — | — | EP | disclosed |
| US-4455314-A | Penicillin derivatives | BEECHAM GROUP P.L.C. (GB) | 1984-06-19 | — | — | US | disclosed |
| EP-0084948-A1 | Penicillin derivatives | BEECHAM GROUP PLC (GB) | 1983-08-03 | — | — | EP | disclosed |
| US-4385060-A | BACTERICIDES AND PROPHYLAXIS | BEECHAM GROUP LIMITED (GB) | 1983-05-24 | — | — | US | disclosed |
| EP-0026644-B1 | ORTHO-TOLYL ESTER OF AN ALPHA-CARBOXY PENICILLIN, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE PENICILLIN | BEECHAM GROUP PLC (GB) | 1982-12-01 | — | — | EP | disclosed |
| EP-0026644-A1 | Ortho-tolyl ester of an alpha-carboxy penicillin, process for its preparation and pharmaceutical compositions comprising the penicillin | BEECHAM GROUP PLC (GB) | 1981-04-08 | — | — | EP | disclosed |