SCHEMBL3939804

SCHEMBL3939804

Cc1ccccc1OC(=O)C(O)C(O)C(=O)Oc1ccccc1C

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
ATM Q13315 1/20 0.49
PPARG P37231 1/20 0.45
BCHE P06276 1/20 0.45
ADRB2 P07550 1/20 0.45
ADRB1 P08588 1/20 0.45
ADRB3 P13945 1/20 0.45
KDM4E B2RXH2 2/20 0.44
CYP1A2 P05177 1/20 0.44
ALOX15 P16050 1/20 0.41
ALDH1A1 P00352 1/20 0.41
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
RXRG P48443 1/20 0.40
NOTUM Q6P988 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17502798 1.00 TDP1 (0.49) TDP1L3MBTL1ATMPPARGBCHE
SCHEMBL30605965 1.00 TDP1 (0.49) TDP1L3MBTL1ATMPPARGBCHE
SCHEMBL3632860 0.93 TDP1 (0.44) TDP1L3MBTL1ATMPPARGBCHE
Methyl Alcohol SCHEMBL27966192 0.91 ADRB2 (0.43) TDP1L3MBTL1ATMPPARGBCHE
Water SCHEMBL27298765 0.91 L3MBTL1 (0.43) TDP1L3MBTL1ATMPPARGBCHE
SCHEMBL27915693 0.88 L3MBTL1 (0.48) TDP1L3MBTL1ATMADRB2ADRB1
SCHEMBL27726032 0.88 TDP1 (0.49) TDP1L3MBTL1ATMPPARGBCHE
SCHEMBL1826831 0.86 TDP1 (0.47) TDP1L3MBTL1ATMPPARGBCHE
SCHEMBL27517150 0.86 CASP1 (0.42) TDP1L3MBTL1ATMPPARGBCHE
SCHEMBL1261877 0.84 MEN1 (0.51) TDP1L3MBTL1ATMPPARGBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250270184-A1 PROCESSES FOR THE PREPARATION OF FINERENONE ASSIA CHEMICAL INDUSTRIES LTD. (IL) 2025-08-28 US disclosed
US-20240316052-A1 MITOCHONDRIAL SUPERCOMPLEX FORMATION PROMOTER, COMPOSITION FOR MAINTAINING OR IMPROVING MUSCULAR STRENGTH, THERAPEUTIC OR PREVENTATIVE PHARMACEUTICAL COMPOSITION FOR DISEASES WHICH DECREASE MITOCHONDRIAL FUNCTION OR MUSCULAR FUNCTION, AND SCREENING METHOD FOR SUBSTANCES WHICH CONTRIBUTE TO FORMATION OF MITOCHONDRIAL SUPERCOMPLEX TOKYO METROPOLITAN GERIATRIC HOSPITAL AND INSTITUTE OF GERONTOLOGY (JP) 2024-09-26 US disclosed
WO-2016108206-A2 PROCESSES FOR PREPARATION OF IDELALISIB AND INTERMEDIATES THEREOF DR. REDDY’S LABORATORIES LIMITED (IN) 2016-07-07 WO disclosed
CN-102351918-B Glucopyranosyl-substituted benzonitrile derivatives and pharmaceutical compositions containing the same BOEHRINGER INGELHEIM INT 2015-03-04 CN disclosed
CN-103601709-A Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture BOEHRINGER INGELHEIM INT 2014-02-26 CN disclosed
CN-101939316-B Spirocyclic heterocyclic compounds, medicaments containing said compounds, their use and processes for their preparation BOEHRINGER INGELHEIM INT 2013-10-02 CN disclosed
CN-102351918-A Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing said compounds, their use and process for their preparation BOEHRINGER INGELHEIM INT 2012-02-15 CN disclosed
CN-102203064-A Novel benzamides, their preparation and their use as medicaments BOEHRINGER INGELHEIM INT 2011-09-28 CN disclosed
US-7544840-B2 Method of production of (−)-(S)-3-[1-(dimethylamino)ethyl]phenyl-N-ethyl-N-methylcarbamate ZENTIVA, A.S. (CZ) 2009-06-09 US disclosed
CN-101437807-A Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing said compounds, their use and process for their preparation BOEHRINGER INGELHEIM INT (DE) 2009-05-20 CN disclosed
EP-1556338-A1 A METHOD OF PRODUCTION OF (-)-(S)-3- 1-(DIMETHYLAMINO)ETHYL& rsqb;PHENYL-N-ETHYL-N-METHYLCARBAMATE Zentiva, A.S. (CZ) 2005-07-27 EP disclosed
CN-1183127-C Alkoxy-substituted benzimidazole compounds, pharmaceutical formulations containing them and methods of using them 2005-01-05 CN disclosed
CN-1509270-A Indolinones substituted in the 6-position, process for their preparation and their use as kinase inhibitors ���ָ��Ӣ��ķ�������Ϲ�˾ 2004-06-30 CN disclosed
WO-2004037771-A1 A METHOD OF PRODUCTION OF (-)-(S)-3-[1-(DIMETHYLAMINO)ETHYL]PHENYL-N-ETHYL-N-METHYLCARBAMATE ZENTIVA, A.S. (CZ) 2004-05-06 WO disclosed
CN-1384831-A Alkoxy-substituted benzimidazole compounds, pharmaceutical formulations containing them and methods of using them EIPHAVMA INC (US) 2002-12-11 CN disclosed
CN-1319090-A Novel substuted indolimones, their preparation process and use as medicine BOEHRINGER INGELHEIM PHARMA (DE) 2001-10-24 CN disclosed
CN-1066445-C Aroyl-piperidine derivatives NOVARTIS AG (CH) 2001-05-30 CN disclosed
CN-1187186-A Substituted phenyl amindines, medicaments containing these compounds and process for producing them THOMAE GMBH DR K (DE) 1998-07-08 CN disclosed
CN-1133839-A Aroyl-piperidine derivatives CIBA GEIGY AG (CH) 1996-10-23 CN disclosed
CN-1087904-A Carboxylic acid derivative, the pharmaceutical composition that contains these compounds with and preparation method thereof KRAL THOMAE GMBH (DE) 1994-06-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250270184-A1 PROCESSES FOR THE PREPARATION OF FINERENONE CYP11B1, CYP11B2, HSD17B7 TDP1 1814/4885L3MBTL1 4788/4885ATM 828/4885
US-20240316052-A1 MITOCHONDRIAL SUPERCOMPLEX FORMATION PROMOTER, COMPOSITION FOR MAINTAINING OR IMPROVING MUSCULAR STRENGTH, THERAPEUTIC OR PREVENTATIVE PHARMACEUTICAL COMPOSITION FOR DISEASES WHICH DECREASE MITOCHONDRIAL FUNCTION OR MUSCULAR FUNCTION, AND SCREENING METHOD FOR SUBSTANCES WHICH CONTRIBUTE TO FORMATION OF MITOCHONDRIAL SUPERCOMPLEX TFAM, MAVS, CKMT1A; CKMT1B TDP1 408/4885L3MBTL1 4102/4885ATM 610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.