Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11664079 | 0.84 | SRC (0.48) | ATML3MBTL1IDO1TDO2SRC | |
| SCHEMBL10818396 | 0.81 | L3MBTL1 (0.38) | ATML3MBTL1IDO1TDO2SRC | |
| SCHEMBL6439691 | 0.81 | SRC (0.61) | ATML3MBTL1SRCELANEMAPT | |
| SCHEMBL10650923 | 0.80 | IDO1 (0.50) | IDO1TDO2SRCCHRNB2CHRNB4 | |
| SCHEMBL162736 | 0.79 | SRC (0.50) | L3MBTL1IDO1TDO2SRCCHRNB2 | |
| SCHEMBL11101690 | 0.79 | ALDH1A1 (0.44) | L3MBTL1ELANEMAPTSLC1A3TDP1 | |
| Hydrochloric Acid SCHEMBL11244144 | 0.77 | SRC (0.48) | IDO1TDO2SRCCHRNB2CHRNB4 | |
| SCHEMBL10918696 | 0.77 | SRC (0.48) | IDO1TDO2SRCCHRNB2CHRNB4 | |
| SCHEMBL11260231 | 0.76 | LMNA (0.41) | IDO1TDO2SRCCHRNB2CHRNB4 | |
| SCHEMBL9814548 | 0.74 | ALOX5 (0.50) | IDO1TDO2SRCCHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4877783-A | β-lactam antibacterial agents | BEECHAM GROUP P.L.C. (GB) | 1989-10-31 | — | — | US | disclosed |
| EP-0071395-B1 | BETA-LACTAM ANTIBACTERIAL AGENTS | BEECHAM GROUP PLC (GB) | 1988-08-10 | — | — | EP | disclosed |
| EP-0098615-B1 | 1-OXADETHIACEPHALOSPORIN COMPOUND AND ANTIBACTERIAL AGENT CONTAINING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 1988-01-07 | — | — | EP | disclosed |
| US-4609652-A | FORMAMIDYL DERIVATIVES OF AMINO ACID DERIVATIVE ANTIBIOTICS | BEECHAM GROUP P.L.C. (GB) | 1986-09-02 | — | — | US | disclosed |
| US-4539149-A | β-Lactam antibacterial agents | BEECHAM GROUP P.L.C. (GB) | 1985-09-03 | — | — | US | disclosed |
| US-4497811-A | BACTERICIDES | MEIJI SEIKA KAISHA, LTD. (JP) | 1985-02-05 | — | — | US | disclosed |
| EP-0098615-A1 | 1-Oxadethiacephalosporin compound and antibacterial agent containing the same | MEIJI SEIKA KAISHA LTD. (JP) | 1984-01-18 | — | — | EP | disclosed |
| EP-0071395-A1 | Beta-lactam antibacterial agents | BEECHAM GROUP PLC (GB) | 1983-02-09 | — | — | EP | disclosed |
| US-4323567-A | BACTERICIDES | NARISADA MASAYUKI | 1982-04-06 | — | — | US | disclosed |
| US-4180571-A | Arylmalonamido-1-oxadethiacephalosporins | SHIONOGI & CO., LTD. (JP) | 1979-12-25 | — | — | US | disclosed |
| US-4138486-A | BACTERICIDES | SHIONOGI & CO., LTD. (JP) | 1979-02-06 | — | — | US | disclosed |