Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | FASN | P49327 | 1/20 | 0.41 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823575 | 0.87 | MEN1 (0.48) | LMNASMN1; SMN2CA2 | |
| SCHEMBL10823443 | 0.84 | MEN1 (0.44) | LMNAGAAPOLBGFERTIMP3 | |
| SCHEMBL10823660 | 0.84 | IDH1 (0.53) | — | |
| SCHEMBL11341737 | 0.82 | TIMP3 (0.50) | DYRK1APOLBTIMP3ENPP2 | |
| SCHEMBL10823413 | 0.81 | PRMT1 (0.53) | LMNATIMP3CA2 | |
| SCHEMBL10823450 | 0.81 | CA2 (0.49) | LMNASMN1; SMN2CA2GPR27 | |
| SCHEMBL10823664 | 0.80 | PTGES (0.47) | LMNADYRK1AGAAPOLBGFER | |
| SCHEMBL10823611 | 0.79 | PRMT1 (0.57) | LMNADYRK1AGAAPOLBGFER | |
| SCHEMBL10823386 | 0.79 | TIMP3 (0.47) | LMNADYRK1AGAAPOLBGFER | |
| SCHEMBL10823696 | 0.79 | TIMP3 (0.47) | LMNADYRK1AGAAPOLBGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |