Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.31 |
| ▸ | OXTR | P30559 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10831640 | 1.00 | ALDH1A1 (0.36) | ALDH1A1TSHRHPGDLMNADRD2 | |
| SCHEMBL10831735 | 0.91 | ALDH1A1 (0.45) | ALDH1A1TSHRHPGDLMNAMAPT | |
| SCHEMBL10832341 | 0.90 | DRD2 (0.38) | ALDH1A1TSHRHPGDLMNADRD2 | |
| SCHEMBL10832346 | 0.90 | DRD2 (0.38) | ALDH1A1TSHRHPGDLMNADRD2 | |
| SCHEMBL10832129 | 0.87 | NPC1 (0.47) | ALDH1A1TSHRHPGDLMNARAB9A | |
| SCHEMBL10832587 | 0.85 | SMN1; SMN2 (0.44) | ALDH1A1TSHRHPGDLMNADRD2 | |
| SCHEMBL10832149 | 0.85 | ALDH1A1 (0.47) | ALDH1A1TSHRHPGDLMNADRD2 | |
| SCHEMBL10880573 | 0.82 | POLB (0.40) | MAPTKMT2APOLBAVPR2AVPR1A | |
| SCHEMBL10832885 | 0.82 | POLB (0.40) | MAPTKMT2APOLBAVPR2AVPR1A | |
| SCHEMBL10831616 | 0.80 | HSD11B1 (0.39) | DRD2DRD3HTR1AP2RX7POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4581460-A | ANALGESICS | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-04-08 | — | — | US | disclosed |
| EP-0083729-B1 | SUBSTITUTED 1-BENZOYL-2-PHENYLIMINO-IMIDAZOLIDINES, THEIR ACID ADDITION SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-02-26 | — | — | EP | disclosed |