Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.35 |
| ▸ | MBTPS1 | Q14703 | 2/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10831645 | 0.91 | ALDH1A1 (0.36) | ALDH1A1LMNAHPGDTSHRTP53 | |
| SCHEMBL10831640 | 0.91 | ALDH1A1 (0.36) | ALDH1A1LMNAHPGDTSHRTP53 | |
| SCHEMBL10832587 | 0.89 | SMN1; SMN2 (0.44) | ALDH1A1LMNAHPGDTSHRGAA | |
| SCHEMBL10831620 | 0.89 | ALDH1A1 (0.45) | ALDH1A1LMNAHPGDTSHRTP53 | |
| SCHEMBL10832129 | 0.86 | NPC1 (0.47) | ALDH1A1LMNAHPGDTSHRTP53 | |
| SCHEMBL10880573 | 0.85 | POLB (0.40) | GAAKMT2AMEN1MAPTPOLB | |
| SCHEMBL10832885 | 0.85 | POLB (0.40) | GAAKMT2AMEN1MAPTPOLB | |
| SCHEMBL10832149 | 0.84 | ALDH1A1 (0.47) | ALDH1A1LMNAHPGDTSHRTP53 | |
| SCHEMBL10831616 | 0.83 | HSD11B1 (0.39) | GAAPOLBKDM4E | |
| SCHEMBL10832323 | 0.82 | PTGS2 (0.42) | ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4581460-A | ANALGESICS | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-04-08 | — | — | US | disclosed |
| EP-0083729-A1 | Substituted 1-benzoyl-2-phenylimino-imidazolidines, their acid addition salts, process for their preparation and pharmaceutical compositions containing them | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1983-07-20 | — | — | EP | disclosed |