Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GPR6 | P46095 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10832129 | 0.89 | NPC1 (0.47) | SMN1; SMN2RAB9AALDH1A1TSHRKMT2A | |
| SCHEMBL10831735 | 0.89 | ALDH1A1 (0.45) | ALDH1A1TSHRKMT2AKDM4EMEN1 | |
| SCHEMBL10832451 | 0.88 | GPR6 (0.45) | SMN1; SMN2RAB9AALDH1A1TSHRMGLL | |
| SCHEMBL10880573 | 0.88 | POLB (0.40) | MGLLKMT2AMEN1MAPTRECQL | |
| SCHEMBL10832885 | 0.88 | POLB (0.40) | MGLLKMT2AMEN1MAPTRECQL | |
| SCHEMBL10832149 | 0.87 | ALDH1A1 (0.47) | SMN1; SMN2RAB9AALDH1A1TSHRKMT2A | |
| SCHEMBL10831616 | 0.86 | HSD11B1 (0.39) | MGLLKDM4EPOLBGPR6DRD2 | |
| SCHEMBL10831640 | 0.85 | ALDH1A1 (0.36) | SMN1; SMN2RAB9AALDH1A1TSHRKMT2A | |
| SCHEMBL10831645 | 0.85 | ALDH1A1 (0.36) | SMN1; SMN2RAB9AALDH1A1TSHRKMT2A | |
| SCHEMBL10832323 | 0.84 | PTGS2 (0.42) | ALDH1A1MGLLPTPN11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4581460-A | ANALGESICS | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-04-08 | — | — | US | claimed |
| US-4581460-A | ANALGESICS | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-04-08 | — | — | US | disclosed |
| EP-0083729-B1 | SUBSTITUTED 1-BENZOYL-2-PHENYLIMINO-IMIDAZOLIDINES, THEIR ACID ADDITION SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-02-26 | — | — | EP | disclosed |
| EP-0083729-A1 | Substituted 1-benzoyl-2-phenylimino-imidazolidines, their acid addition salts, process for their preparation and pharmaceutical compositions containing them | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1983-07-20 | — | — | EP | disclosed |