Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | GPR6 | P46095 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 10/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10832885 | 1.00 | POLB (0.40) | POLBAVPR2AVPR1AGPR6MGLL | |
| SCHEMBL10831616 | 0.91 | HSD11B1 (0.39) | POLBGPR6MGLLGAA | |
| SCHEMBL10831688 | 0.89 | SLC6A7 (0.37) | MAPTGAA | |
| SCHEMBL10832587 | 0.88 | SMN1; SMN2 (0.44) | POLBGPR6MGLLMEN1KMT2A | |
| SCHEMBL10832323 | 0.87 | PTGS2 (0.42) | MGLL | |
| SCHEMBL10831829 | 0.87 | MGLL (0.43) | MGLLKMT2AMAPTGAARECQL | |
| SCHEMBL10832640 | 0.86 | GPR6 (0.43) | POLBAVPR2AVPR1AGPR6MGLL | |
| SCHEMBL10831735 | 0.85 | ALDH1A1 (0.45) | POLBMEN1KMT2AMAPTGAA | |
| SCHEMBL10832129 | 0.85 | NPC1 (0.47) | POLBMEN1KMT2AMAPTGAA | |
| SCHEMBL10832398 | 0.84 | GAA (0.45) | GPR6MGLLGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0083729-B1 | SUBSTITUTED 1-BENZOYL-2-PHENYLIMINO-IMIDAZOLIDINES, THEIR ACID ADDITION SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-02-26 | — | — | EP | disclosed |