Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10841715 | 0.89 | THRB (0.45) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL10842650 | 0.86 | NPSR1 (0.53) | MEN1KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL10842811 | 0.84 | NPBWR1 (0.42) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL10841737 | 0.83 | THRB (0.61) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL10842636 | 0.80 | POLB (0.51) | MEN1KMT2ASMN1; SMN2CHEK1RAB9A | |
| SCHEMBL13844340 | 0.68 | RAB9A (0.54) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL6118115 | 0.67 | SCN5A (0.45) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL10842419 | 0.67 | KDM4E (0.36) | MEN1KMT2ASMN1; SMN2CHEK1NPC1 | |
| SCHEMBL3974325 | 0.67 | APP (0.74) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL2455303 | 0.67 | APP (0.74) | MEN1KMT2ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174833-A2 | Triazoloquinoline derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |