Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.39 |
| ▸ | NPC1 | O15118 | 10/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10849969 | 0.89 | ALDH1A1 (0.44) | RAB9ANPC1SMN1; SMN2CYP1A2POLB | |
| SCHEMBL10849021 | 0.86 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2CYP1A2POLB | |
| SCHEMBL10849346 | 0.72 | ALDH1A1 (0.42) | RAB9ANPC1SMN1; SMN2CYP1A2POLB | |
| Hydrochloric Acid SCHEMBL11214622 | 0.72 | ALDH1A1 (0.41) | RAB9ANPC1SMN1; SMN2CYP1A2POLB | |
| SCHEMBL10851145 | 0.71 | GAA (0.45) | RAB9ANPC1SMN1; SMN2CYP1A2POLB | |
| SCHEMBL10850376 | 0.70 | ALDH1A1 (0.44) | RAB9ANPC1SMN1; SMN2CYP1A2POLB | |
| SCHEMBL10846141 | 0.69 | NPC1 (0.45) | RAB9ANPC1SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL9033466 | 0.64 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2CYP1A2POLB | |
| SCHEMBL27645217 | 0.63 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2CYP1A2POLB | |
| SCHEMBL7721905 | 0.63 | L3MBTL1 (0.40) | SMN1; SMN2POLBALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4622401-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1986-11-11 | — | — | US | disclosed |