SCHEMBL10851027

SCHEMBL10851027

O=[N+]([O-])c1ccc(S(=O)(=O)N2C(O)c3ccccc3C2O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.52
MMP2 P08253 3/20 0.50
PARL Q9H300 1/20 0.46
NOD1 Q9Y239 1/20 0.44
CTSG P08311 1/20 0.44
CMA1 P23946 1/20 0.44
CA2 P00918 4/20 0.44
CA1 P00915 3/20 0.44
MAPT P10636 1/20 0.44
MMP1 P03956 1/20 0.44
MMP9 P14780 1/20 0.44
MMP8 P22894 1/20 0.44
MMP13 P45452 1/20 0.44
CA12 O43570 3/20 0.43
CA9 Q16790 3/20 0.43
CA3 P07451 2/20 0.43
CA4 P22748 2/20 0.43
CA6 P23280 2/20 0.43
CA5A P35218 2/20 0.43
CA7 P43166 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13998284 0.83 ACHE (0.54) ACHEMMP2PARLNOD1CTSG
SCHEMBL11165160 0.81 ACHE (0.49) ACHEMMP2PARLALDH1A1KMT2A
SCHEMBL10855067 0.79 PSEN1 (0.49) ACHEMMP2ALDH1A1KMT2A
SCHEMBL10856085 0.79 MMP2 (0.46) MMP2CTSGCMA1CA2CA1
SCHEMBL9326548 0.79 ACHE (0.50) ACHEMMP2CA2CA1
SCHEMBL32674218 0.75 ACHE (0.56) ACHEMMP2PARLCA2CA1
SCHEMBL11162173 0.74 HSD11B1 (0.37) ACHENOD1CA2CA1CA12
SCHEMBL5832337 0.72 ACHE (0.74) ACHEMMP2PARLCA2CA1
SCHEMBL10858693 0.72 POLB (0.59) MMP2CA2CA1MAPTMMP1
SCHEMBL6981036 0.70 MMP2 (0.54) ACHEMMP2CTSGCMA1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4596876-A Isoindoline compounds EASTMAN KODAK COMPANY (US) 1986-06-24 US claimed
EP-0067714-A2 Phthalaldehyde adduct and image-forming compositions incorporating the same EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1982-12-22 EP claimed
US-4410623-A COBALT (III) COMPLEX WITH AMINE LIGAND EASTMAN KODAK COMPANY (US) 1983-10-18 US disclosed