SCHEMBL9326548

SCHEMBL9326548

Cc1ccc(S(=O)(=O)N2C(O)c3ccccc3C2O)cc1

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.50
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
TERT O14746 1/20 0.48
MMP2 P08253 2/20 0.46
NPSR1 Q6W5P4 1/20 0.46
GAA P10253 1/20 0.46
FFAR4 Q5NUL3 1/20 0.44
P2RX4 Q99571 1/20 0.44
PKM P14618 1/20 0.43
LMNA P02545 1/20 0.43
HTR6 P50406 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11165160 0.85 ACHE (0.49) ACHETERTMMP2LMNAHTR6
SCHEMBL10860402 0.83 MMP2 (0.39) ACHECA1CA2TERTMMP2
SCHEMBL10856085 0.83 MMP2 (0.46) CA1CA2MMP2PKMLMNA
SCHEMBL10855067 0.83 PSEN1 (0.49) ACHEMMP2PKMLMNA
SCHEMBL11162173 0.81 HSD11B1 (0.37) ACHECA1CA2TERTPKM
SCHEMBL13998283 0.81 ACHE (0.51) ACHECA1CA2TERTMMP2
SCHEMBL10851027 0.79 ACHE (0.52) ACHECA1CA2MMP2
SCHEMBL10851226 0.79 FBP1 (0.58) CA1CA2GAALMNA
SCHEMBL10858693 0.79 POLB (0.59) CA1CA2MMP2NPSR1PKM
SCHEMBL28735103 0.74 LMNA (0.52) CA1CA2TERTMMP2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4596876-A Isoindoline compounds EASTMAN KODAK COMPANY (US) 1986-06-24 US claimed
EP-0067714-A2 Phthalaldehyde adduct and image-forming compositions incorporating the same EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1982-12-22 EP claimed
EP-0449969-B1 PHOTORESIST COMPOSITIONS CONTAINING COBALT (III) COMPOUND AND REDOX TRANSFER LIGAND EASTMAN KODAK CO (US) 1994-02-16 EP disclosed
US-4596876-A Isoindoline compounds EASTMAN KODAK COMPANY (US) 1986-06-24 US disclosed
US-4410623-A COBALT (III) COMPLEX WITH AMINE LIGAND EASTMAN KODAK COMPANY (US) 1983-10-18 US disclosed
EP-0067714-A2 Phthalaldehyde adduct and image-forming compositions incorporating the same EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1982-12-22 EP disclosed